Q9LIS3 · GAE6_ARATH

Function

function

Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components.

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.23 mMUDP-glucuronate
No activity with UDP-Galactose, UDP- Glucose or UDP-Xylose.

pH Dependence

Optimum pH is 7.9. Active from pH 6 to 8.9.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site113-144NAD+ (UniProtKB | ChEBI)
Active site263Proton acceptor

GO annotations

AspectTerm
Cellular Componentendosome
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi cisterna membrane
Cellular ComponentGolgi trans cisterna
Cellular Componenttrans-Golgi network
Molecular FunctionUDP-glucuronate 4-epimerase activity
Biological Processdefense response to fungus
Biological Processdefense response to Gram-negative bacterium
Biological Processgalacturonate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-glucuronate 4-epimerase 6
  • EC number
  • Alternative names
    • UDP-glucuronic acid epimerase 6 (AtUGlcAE2)

Gene names

    • Name
      GAE6
    • Synonyms
      UGlcAE2
    • ORF names
      F14O13.1
    • Ordered locus names
      At3g23820

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9LIS3
  • Secondary accessions
    • Q8H7G2

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane41-61Helical
Transmembrane111-131Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002926011-460UDP-glucuronate 4-epimerase 6

Proteomic databases

PTM databases

Expression

Tissue specificity

In roots, leaf veins, siliques, flowers, pollen and stems.

Gene expression databases

Interaction

Subunit

Homodimer.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY Q9LIS3CPK4 Q388694EBI-2297116, EBI-979475

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    460
  • Mass (Da)
    50,570
  • Last updated
    2000-10-01 v1
  • MD5 Checksum
    7B2F7E66ABD551C2AA9EC66585D5320F
MPLSATADTSKTVKLERYNSYLRKIHSTKVLNASSKVLFRATLLVALVLVLIFAINYPPLSDSRAAAAHHLHRRSFLSTGLFSSSSSSSSIGGAAWEKRVRQSSTAKRPHGLSVLVTGAAGFVGSHCSLALRKRGDGVLGFDNFNDYYDPSLKRARQELLEKQQVFIVEGDLNDGPLLRKLFDVVPFTHILHLAAQAGVRYAMKNPQSYIASNIAGFVNLLEVAKAANPQPAIVWASSSSVYGLNTENPFSEEHRTDQPASLYAATKKAGEEIAHTYNHIYGLSLTGLRFFTVYGPWGRPDMAYFFFTKDILHGKSIDIYRTQDNQEVARDFTYIDDIVKGCVGALDTAEKSTGSGGKKRGQAQLRVYNLGNTSPVPVGRLVSILEGLLGTKAKKHLIKMPRNGDVPYTHANVSLAYKDFGYKPTTDLAAGLRKFVKWYVGYYGIQPRVKKETSHAEDSA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ879893
EMBL· GenBank· DDBJ
CAI53858.1
EMBL· GenBank· DDBJ
Genomic DNA
AP001297
EMBL· GenBank· DDBJ
BAB03000.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE76818.1
EMBL· GenBank· DDBJ
Genomic DNA
AF083691
EMBL· GenBank· DDBJ
AAN60250.1
EMBL· GenBank· DDBJ
mRNA
AF370210
EMBL· GenBank· DDBJ
AAK44025.1
EMBL· GenBank· DDBJ
mRNA
AY056117
EMBL· GenBank· DDBJ
AAL07003.1
EMBL· GenBank· DDBJ
mRNA
AY062625
EMBL· GenBank· DDBJ
AAL32703.1
EMBL· GenBank· DDBJ
mRNA
AY133771
EMBL· GenBank· DDBJ
AAM91705.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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