Q9LFX9 · PTR13_ARATH
- ProteinProtein NRT1/ PTR FAMILY 2.12
- GeneNPF2.12
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids576 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Low-affinity proton-dependent nitrate transporter. Not involved in dipeptides transport. Involved in delivering nitrate for seed development.
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
6 mM | nitrate at -60 mV |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | low-affinity nitrate transmembrane transporter activity | |
Molecular Function | symporter activity | |
Biological Process | cellular response to nitrogen levels | |
Biological Process | embryo development ending in seed dormancy | |
Biological Process | nitrate assimilation | |
Biological Process | nitrate transmembrane transport | |
Biological Process | oligopeptide transport | |
Biological Process | seed development | |
Biological Process | suspensor development |
Keywords
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameProtein NRT1/ PTR FAMILY 2.12
- Short namesAtNPF2.12
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9LFX9
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 58-78 | Helical | ||||
Sequence: FNVYYLWMGLTNFAPLLGALI | ||||||
Transmembrane | 89-109 | Helical | ||||
Sequence: IAYASLFSILGLMTVTLTACL | ||||||
Transmembrane | 130-150 | Helical | ||||
Sequence: KLQLGILFLGLGFLSIGSGGI | ||||||
Transmembrane | 176-196 | Helical | ||||
Sequence: FFNWYYLTLTMVLIFSHTVVV | ||||||
Transmembrane | 203-223 | Helical | ||||
Sequence: WVIGFSIPTSLMACAVVLFFV | ||||||
Transmembrane | 329-349 | Helical | ||||
Sequence: VWSAGIISIVAMTTQATFMVF | ||||||
Transmembrane | 364-384 | Helical | ||||
Sequence: IPAASITVISYITIGIWVPIY | ||||||
Transmembrane | 406-426 | Helical | ||||
Sequence: MGIGIVFAILSMFTAGFVEGV | ||||||
Transmembrane | 441-461 | Helical | ||||
Sequence: WLALPLILMGLCESFNFIGLI | ||||||
Transmembrane | 475-495 | Helical | ||||
Sequence: IANSLFPLSFAAANYLSSLLV | ||||||
Transmembrane | 522-542 | Helical | ||||
Sequence: YFYYLIAVLGVVNLVYFWYCA |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Aberrant embryo development and increased seed abortion. Reduced seed nitrate content.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 67 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000399947 | 1-576 | Protein NRT1/ PTR FAMILY 2.12 | |||
Sequence: MGVVENRKILPEKKLGGWRAITFILGNETLEKLGSIGVSANFMLYLRNVFHMEPVEAFNVYYLWMGLTNFAPLLGALISDAYIGRFKTIAYASLFSILGLMTVTLTACLPQLHPPPCNNPHPDECDDPNKLQLGILFLGLGFLSIGSGGIRPCSIPFGVDQFDQRTEQGLKGVASFFNWYYLTLTMVLIFSHTVVVYLQTVSWVIGFSIPTSLMACAVVLFFVGMRFYVYVKPEGSVFSGIARVIVAARKKRDLKISLVDDGTEEYYEPPVKPGVLSKLPLTDQFKFLDKAAVILDGDLTSEGVPANKWRLCSIQEVEEVKCLIRVVPVWSAGIISIVAMTTQATFMVFQATKMDRHMGPHFEIPAASITVISYITIGIWVPIYEHLLVPFLWRMRKFRVTLLQRMGIGIVFAILSMFTAGFVEGVRRTRATEMTQMSVFWLALPLILMGLCESFNFIGLIEFFNSQFPEHMRSIANSLFPLSFAAANYLSSLLVTTVHKVSGTKDHPDWLNKDLDRGKLDYFYYLIAVLGVVNLVYFWYCAHRYQYKAGSQIEDFNEEKSLLDIEPNQRHDQSPS |
Proteomic databases
Expression
Tissue specificity
Expressed in flowers and siliques. Expressed in vascular bundle of the siliques and in funiculus.
Induction
Up-regulated by nitrogen starvation.
Developmental stage
Expression increases after pollination.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length576
- Mass (Da)64,930
- Last updated2010-11-02 v2
- Checksum6FC3419448D76298
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8AS80 | A0A1P8AS80_ARATH | NPF212 | 534 |
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EU266070 EMBL· GenBank· DDBJ | ABX61048.1 EMBL· GenBank· DDBJ | mRNA | ||
AC000348 EMBL· GenBank· DDBJ | AAF79856.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE30777.1 EMBL· GenBank· DDBJ | Genomic DNA |