Q9LEM9 · DES6_CERPU

Function

function

Fatty acid desaturase able to introduce a delta6-double bond into delta9-unsaturated fatty-acid substrates. Has a strong preference for linoleic acid (18:2(9Z,12Z)).

Catalytic activity

Pathway

Lipid metabolism; polyunsaturated fatty acid biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site132Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue
Binding site154Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acyl-lipid (9-3)-desaturase
  • EC number
  • Alternative names
    • Delta 6-fatty acid desaturase
      (CpDES6
      )

Organism names

Accessions

  • Primary accession
    Q9LEM9

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane22-42Helical
Transmembrane203-223Helical
Transmembrane229-249Helical
Transmembrane261-281Helical
Transmembrane337-357Helical
Transmembrane373-393Helical
Transmembrane396-416Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004354591-520Acyl-lipid (9-3)-desaturase

Structure

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain97-171Cytochrome b5 heme-binding
Motif249-253Histidine box-1
Motif286-290Histidine box-2
Motif457-461Histidine box-3

Domain

The histidine box domains may contain the active site and/or be involved in metal ion binding.

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    520
  • Mass (Da)
    59,160
  • Last updated
    2000-10-01 v1
  • Checksum
    5A9332EECC153439
MVSQGGGLSQGSIEENIDVEHLATMPLVSDFLNVLGTTLGQWSLSTTFAFKRLTTKKHSSDISVEAQKESVARGPVENISQSVAQPIRRRWVQDKKPVTYSLKDVASHDMPQDCWIIIKEKVYDVSTFAEQHPGGTVINTYFGRDATDVFSTFHASTSWKILQNFYIGNLVREEPTLELLKEYRELRALFLREQLFKSSKSYYLFKTLINVSIVATSIAIISLYKSYRAVLLSASLMGLFIQQCGWLSHDFLHHQVFETRWLNDVVGYVVGNVVLGFSVSWWKTKHNLHHAAPNECDQKYTPIDEDIDTLPIIAWSKDLLATVESKTMLRVLQYQHLFFLVLLTFARASWLFWSAAFTLRPELTLGEKLLERGTMALHYIWFNSVAFYLLPGWKPVVWMVVSELMSGFLLGYVFVLSHNGMEVYNTSKDFVNAQIASTRDIKAGVFNDWFTGGLNRQIEHHLFPTMPRHNLNKISPHVETLCKKHGLVYEDVSMASGTYRVLKTLKDVADAASHQQLAAS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ250735
EMBL· GenBank· DDBJ
CAB94993.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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