Q9LEI9 · ENO2_HEVBR

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Mg2+ is required for catalysis and for stabilizing the dimer.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.

Features

Showing features for binding site, active site.

144550100150200250300350400
Type
IDPosition(s)Description
Binding site164substrate
Binding site173substrate
Active site216Proton donor
Binding site251Mg2+ (UniProtKB | ChEBI)
Binding site301Mg2+ (UniProtKB | ChEBI)
Binding site301substrate
Binding site328Mg2+ (UniProtKB | ChEBI)
Binding site328substrate
Active site353Proton acceptor
Binding site380-383substrate
Binding site404substrate

GO annotations

AspectTerm
Cellular Componentphosphopyruvate hydratase complex
Molecular Functionmagnesium ion binding
Molecular Functionphosphopyruvate hydratase activity
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Enolase 2
  • EC number
  • Alternative names
    • 2-phospho-D-glycerate hydro-lyase 2
    • 2-phosphoglycerate dehydratase 2
  • Allergen name
    Hev b 9

Gene names

    • Name
      ENO2

Organism names

Accessions

  • Primary accession
    Q9LEI9

Subcellular Location

Keywords

Phenotypes & Variants

Allergenic properties

Causes an allergic reaction in human. Involved in latex allergic reactions.

Keywords

Protein family/group databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001340701-445Enolase 2

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the enolase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    445
  • Mass (Da)
    47,914
  • Last updated
    2000-10-01 v1
  • Checksum
    C5B42954F0E83EC8
MAITIVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPRGASTGIYEALELRDGGSDYLGKGVSKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAVCKAGAHVKGIPLYKHVANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTGKVVIGMDVAASEFYGSDKTYDLNFKEENNNGSQKISGDVLKDLYKSFVTEYPIVSIEDPFDQDDWEHYAKLTSEIGVKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTESIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLRIEEELGAEAVYAGANFRTPVEPY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ132581
EMBL· GenBank· DDBJ
CAC00533.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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