Q9L6R5 · WECB_SALTY
- ProteinUDP-N-acetylglucosamine 2-epimerase
- GenewecB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids376 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
Catalytic activity
- UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-mannosamine
Pathway
Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 10 | substrate | ||||
Sequence: R | ||||||
Binding site | 15 | substrate | ||||
Sequence: K | ||||||
Binding site | 95 | substrate | ||||
Sequence: D | ||||||
Binding site | 117 | substrate | ||||
Sequence: E | ||||||
Binding site | 213 | substrate | ||||
Sequence: H | ||||||
Binding site | 271 | substrate | ||||
Sequence: Q | ||||||
Binding site | 276 | substrate | ||||
Sequence: F | ||||||
Binding site | 290-292 | substrate | ||||
Sequence: SGG | ||||||
Binding site | 296 | substrate | ||||
Sequence: E | ||||||
Binding site | 313 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | UDP-N-acetylglucosamine 2-epimerase activity | |
Biological Process | enterobacterial common antigen biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylglucosamine 2-epimerase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionQ9L6R5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000208530 | 1-376 | UDP-N-acetylglucosamine 2-epimerase | |||
Sequence: MKVLTVFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLDQVLTLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILADFKPDVVLVHGDTTTTIATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLRENIPDERIFVTGNTVIDALIWVRDRVLTSDTLQAELAEQYPFLNANKKMILVTGHRRESFGQGFEHICQALAEIAAANQNVQIVYPVHLNPNVSEPVNRILGHVENVVLIEPQDYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRETTERPEAITAGTVRLIGTDSRRIVAEVMRLLHDENEYQTMSRAHNPYGDGQSCARILQALKSYRVSL |
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length376
- Mass (Da)42,165
- Last updated2000-10-01 v1
- ChecksumA709B6083C57EE87
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006468 EMBL· GenBank· DDBJ | AAL22769.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF233324 EMBL· GenBank· DDBJ | AAF33467.1 EMBL· GenBank· DDBJ | Genomic DNA |