Q9K6I0 · MURA1_HALH5
- ProteinUDP-N-acetylglucosamine 1-carboxyvinyltransferase 1
- GenemurA1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids440 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
Catalytic activity
- phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 22-23 | phosphoenolpyruvate (UniProtKB | ChEBI) | ||||
Sequence: KN | ||||||
Binding site | 93 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 117 | Proton donor | ||||
Sequence: C | ||||||
Binding site | 122-126 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: RPIDQ | ||||||
Binding site | 306 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 328 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | ||||
Sequence: V |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape | |
Biological Process | UDP-N-acetylgalactosamine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylglucosamine 1-carboxyvinyltransferase 1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Halalkalibacterium (ex Joshi et al. 2022)
Accessions
- Primary accessionQ9K6I0
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000178846 | 1-440 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 | |||
Sequence: MEKIIVRGGRQLSGSVKVEGAKNAVLPVIAASILASRGTSKIYDVPKLADVYTMKEVLRNLNINVEYENGEFVVNATNPLKTEAPFEYVRKMRASFLVMGPLLARVGHARIALPGGCAIGSRPIDQHLKGFEAMGATVEIGNGFIEAKVEGRLQGTKIYLDFPSVGATENIMMAAAMAEGTTILENAAEEPEIVCLANYLNAMGAKVRGAGTGVIRIEGVDELVGAEHTVISDRIEAGTFMVAAAITGGDVFIEGAVAEHLRPLIAKMHEMGVKTIEEDNGIRVIGPDELKPVDIKTMPHPGFPTDMQSQMMALLLRANGTSVITETVFENRFMHVEEFRRMNGNIKIEGRSAIISGPCQLQGAEVTATDLRAGAALVLAGLVADGHTRVVELKHVDRGYVDLAGKLARLGADIERVVETEHELENLDAPAPLKLNTNLV | ||||||
Modified residue | 117 | 2-(S-cysteinyl)pyruvic acid O-phosphothioketal | ||||
Sequence: C |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length440
- Mass (Da)47,193
- Last updated2000-10-01 v1
- ChecksumFFFB2CA82189C2FD
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000004 EMBL· GenBank· DDBJ | BAB07468.1 EMBL· GenBank· DDBJ | Genomic DNA |