Q9JLM4 · ZMYM3_MOUSE
- ProteinZinc finger MYM-type protein 3
- GeneZmym3
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids1370 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Plays a role in the regulation of cell morphology and cytoskeletal organization.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleoplasm | |
Cellular Component | nucleus | |
Molecular Function | zinc ion binding | |
Biological Process | cytoskeleton organization | |
Biological Process | regulation of cell morphogenesis |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameZinc finger MYM-type protein 3
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ9JLM4
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue, cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000191379 | 1-1370 | Zinc finger MYM-type protein 3 | |||
Sequence: MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTYSKKPLGRKTCTFCKKEIWNTKDSVVVQTGPGGSFHEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGGLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQHTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDENGNLGKTPVKRATPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKAEMKSKGSQTEEWKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLMLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGETSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD | ||||||
Modified residue | 265 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 269 | Phosphoserine | ||||
Sequence: S | ||||||
Cross-link | 310 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 322 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 330 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 780 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 788 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Modified residue | 797 | Phosphothreonine | ||||
Sequence: T | ||||||
Cross-link | 806 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Modified residue | 818 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 827 | Phosphothreonine | ||||
Sequence: T | ||||||
Cross-link | 848 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 862 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 921 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K | ||||||
Cross-link | 1276 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Ubiquitously expressed in all embryonic stages and adult tissues.
Gene expression databases
Interaction
Subunit
May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
XENO | Q9JLM4 | GTF2IRD1 Q9UHL9 | 3 | EBI-12517169, EBI-372530 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for region, compositional bias, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-73 | Disordered | ||||
Sequence: MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGV | ||||||
Region | 85-310 | Disordered | ||||
Sequence: GLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTK | ||||||
Compositional bias | 120-134 | Pro residues | ||||
Sequence: QTPEVMPPDPGAGAS | ||||||
Compositional bias | 161-176 | Basic and acidic residues | ||||
Sequence: EIPPLATRRRGSPGQE | ||||||
Compositional bias | 198-214 | Polar residues | ||||
Sequence: TLGDGINSSQSKPGVCT | ||||||
Compositional bias | 229-254 | Basic and acidic residues | ||||
Sequence: KEIEKPPERVQKRSERVRRAEPPKPE | ||||||
Compositional bias | 261-277 | Acidic residues | ||||
Sequence: SIPVSDEDSDAMVDDPN | ||||||
Compositional bias | 293-307 | Polar residues | ||||
Sequence: SLRSSMAQRAGRSSM | ||||||
Zinc finger | 334-368 | MYM-type 1 | ||||
Sequence: QLFCSSSCLTTYSKKPLGRKTCTFCKKEIWNTKDS | ||||||
Zinc finger | 380-424 | MYM-type 2 | ||||
Sequence: HEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEV | ||||||
Zinc finger | 431-466 | MYM-type 3 | ||||
Sequence: HRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGG | ||||||
Zinc finger | 479-513 | MYM-type 4 | ||||
Sequence: KRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEML | ||||||
Zinc finger | 523-561 | MYM-type 5 | ||||
Sequence: SLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYY | ||||||
Zinc finger | 569-606 | MYM-type 6 | ||||
Sequence: YQFCSPSCWTKFQHTSPEGGIHLSCHYCHSLFSGKPEV | ||||||
Zinc finger | 614-648 | MYM-type 7 | ||||
Sequence: FQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKL | ||||||
Zinc finger | 655-694 | MYM-type 8 | ||||
Sequence: KSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTE | ||||||
Zinc finger | 701-735 | MYM-type 9 | ||||
Sequence: WDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETI | ||||||
Compositional bias | 761-801 | Polar residues | ||||
Sequence: NLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDEN | ||||||
Region | 761-831 | Disordered | ||||
Sequence: NLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDENGNLGKTPVKRATPSVPTPPPPPPPATPRKN | ||||||
Compositional bias | 813-829 | Pro residues | ||||
Sequence: TPSVPTPPPPPPPATPR |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,370
- Mass (Da)152,879
- Last updated2000-10-01 v1
- ChecksumE9270E68366E46F1
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 120-134 | Pro residues | ||||
Sequence: QTPEVMPPDPGAGAS | ||||||
Compositional bias | 161-176 | Basic and acidic residues | ||||
Sequence: EIPPLATRRRGSPGQE | ||||||
Compositional bias | 198-214 | Polar residues | ||||
Sequence: TLGDGINSSQSKPGVCT | ||||||
Compositional bias | 229-254 | Basic and acidic residues | ||||
Sequence: KEIEKPPERVQKRSERVRRAEPPKPE | ||||||
Sequence conflict | 238-239 | in Ref. 2; BAC65550 | ||||
Sequence: Missing | ||||||
Compositional bias | 261-277 | Acidic residues | ||||
Sequence: SIPVSDEDSDAMVDDPN | ||||||
Compositional bias | 293-307 | Polar residues | ||||
Sequence: SLRSSMAQRAGRSSM | ||||||
Sequence conflict | 493-495 | in Ref. 2; BAC65550 | ||||
Sequence: KNT → VGP | ||||||
Sequence conflict | 719-735 | in Ref. 2; BAC65550 | ||||
Sequence: AARCHACKRQGKLLETI → VRRVNRAERRQQGDELW | ||||||
Compositional bias | 761-801 | Polar residues | ||||
Sequence: NLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDEN | ||||||
Compositional bias | 813-829 | Pro residues | ||||
Sequence: TPSVPTPPPPPPPATPR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF156605 EMBL· GenBank· DDBJ | AAF37800.1 EMBL· GenBank· DDBJ | mRNA | ||
AK122268 EMBL· GenBank· DDBJ | BAC65550.3 EMBL· GenBank· DDBJ | Transcribed RNA | Different initiation |