Q9JLM4 · ZMYM3_MOUSE

  • Protein
    Zinc finger MYM-type protein 3
  • Gene
    Zmym3
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

function

Plays a role in the regulation of cell morphology and cytoskeletal organization.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Cellular Componentnucleus
Molecular Functionzinc ion binding
Biological Processcytoskeleton organization
Biological Processregulation of cell morphogenesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Zinc finger MYM-type protein 3
  • Alternative names
    • DXHXS6673E protein
    • Zinc finger protein 261

Gene names

    • Name
      Zmym3
    • Synonyms
      Kiaa0385, Zfp261, Znf261

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9JLM4
  • Secondary accessions
    • Q80U17

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue, cross-link.

TypeIDPosition(s)Description
ChainPRO_00001913791-1370Zinc finger MYM-type protein 3
Modified residue265Phosphoserine
Modified residue269Phosphoserine
Cross-link310Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link322Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link330Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link780Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link788Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Modified residue797Phosphothreonine
Cross-link806Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Modified residue818Phosphothreonine
Modified residue827Phosphothreonine
Cross-link848Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link862Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link921Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Cross-link1276Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Ubiquitously expressed in all embryonic stages and adult tissues.

Gene expression databases

Interaction

Subunit

May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
XENO Q9JLM4GTF2IRD1 Q9UHL93EBI-12517169, EBI-372530

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias, zinc finger.

TypeIDPosition(s)Description
Region1-73Disordered
Region85-310Disordered
Compositional bias120-134Pro residues
Compositional bias161-176Basic and acidic residues
Compositional bias198-214Polar residues
Compositional bias229-254Basic and acidic residues
Compositional bias261-277Acidic residues
Compositional bias293-307Polar residues
Zinc finger334-368MYM-type 1
Zinc finger380-424MYM-type 2
Zinc finger431-466MYM-type 3
Zinc finger479-513MYM-type 4
Zinc finger523-561MYM-type 5
Zinc finger569-606MYM-type 6
Zinc finger614-648MYM-type 7
Zinc finger655-694MYM-type 8
Zinc finger701-735MYM-type 9
Compositional bias761-801Polar residues
Region761-831Disordered
Compositional bias813-829Pro residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,370
  • Mass (Da)
    152,879
  • Last updated
    2000-10-01 v1
  • Checksum
    E9270E68366E46F1
MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTYSKKPLGRKTCTFCKKEIWNTKDSVVVQTGPGGSFHEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGGLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQHTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDENGNLGKTPVKRATPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKAEMKSKGSQTEEWKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLMLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGETSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
B0R077B0R077_MOUSEZmym3495
B1AXS6B1AXS6_MOUSEZmym31278
B1AXS7B1AXS7_MOUSEZmym31368
B1AXS8B1AXS8_MOUSEZmym31356
B1AXS9B1AXS9_MOUSEZmym3113
Q32P02Q32P02_MOUSEZmym3349
Q8CG95Q8CG95_MOUSEZmym3497

Sequence caution

The sequence BAC65550.3 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias120-134Pro residues
Compositional bias161-176Basic and acidic residues
Compositional bias198-214Polar residues
Compositional bias229-254Basic and acidic residues
Sequence conflict238-239in Ref. 2; BAC65550
Compositional bias261-277Acidic residues
Compositional bias293-307Polar residues
Sequence conflict493-495in Ref. 2; BAC65550
Sequence conflict719-735in Ref. 2; BAC65550
Compositional bias761-801Polar residues
Compositional bias813-829Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF156605
EMBL· GenBank· DDBJ
AAF37800.1
EMBL· GenBank· DDBJ
mRNA
AK122268
EMBL· GenBank· DDBJ
BAC65550.3
EMBL· GenBank· DDBJ
Transcribed RNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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