Q9JJA7 · CCNL2_MOUSE
- ProteinCyclin-L2
- GeneCcnl2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids518 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
rs219640923 | 9 | A>S | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.68) Somatic: No Accession: NC_000070.7:g.155897009G>T Codon: GCG/TCG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897009G>T Locations: - p.Ala9Ser (Ensembl:ENSMUST00000030944) - c.25G>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs52568760 | 16 | S>A | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: NC_000070.7:g.155897030T>G Codon: TCG/GCG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897030T>G Locations: - p.Ser16Ala (Ensembl:ENSMUST00000030944) - c.46T>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs257666848 | 16 | S>L | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.29) Somatic: No Accession: NC_000070.7:g.155897031C>T Codon: TCG/TTG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897031C>T Locations: - p.Ser16Leu (Ensembl:ENSMUST00000030944) - c.47C>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3543115480 | 30 | S>A | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.49) Somatic: No Accession: NC_000070.7:g.155897072T>G Codon: TCT/GCT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897072T>G Locations: - p.Ser30Ala (Ensembl:ENSMUST00000030944) - c.88T>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3543155935 | 33 | V>G | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000070.7:g.155897082T>G Codon: GTG/GGG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897082T>G Locations: - p.Val33Gly (Ensembl:ENSMUST00000030944) - c.98T>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs250110218 | 69 | V>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.38) Somatic: No Accession: NC_000070.7:g.155897189G>A Codon: GTC/ATC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897189G>A Locations: - p.Val69Ile (Ensembl:ENSMUST00000030944) - c.205G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388740256 | 79 | G>D | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000070.7:g.155897220G>A Codon: GGC/GAC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155897220G>A Locations: - p.Gly79Asp (Ensembl:ENSMUST00000030944) - c.236G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388734993 | 159 | V>M | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.09) Somatic: No Accession: NC_000070.7:g.155899707G>A Codon: GTG/ATG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155899707G>A Locations: - p.Val159Met (Ensembl:ENSMUST00000030944) - c.475G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388737385 | 168 | V>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: NC_000070.7:g.155899734G>A Codon: GTT/ATT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155899734G>A Locations: - p.Val168Ile (Ensembl:ENSMUST00000030944) - c.502G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388743883 | 226 | R>G | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000070.7:g.155904808C>G Codon: CGC/GGC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155904808C>G Locations: - p.Arg226Gly (Ensembl:ENSMUST00000030944) - c.676C>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs33200589 | 247 | A>G | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000070.7:g.155904872C>G Codon: GCC/GGC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155904872C>G Locations: - p.Ala247Gly (Ensembl:ENSMUST00000030944) - c.740C>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs33202454 | 317 | T>S | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.12) Somatic: No Accession: NC_000070.7:g.155905521C>G Codon: ACT/AGT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155905521C>G Locations: - p.Thr317Ser (Ensembl:ENSMUST00000030944) - c.950C>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs245378324 | 337 | K>E | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: NC_000070.7:g.155906277A>G Codon: AAA/GAA Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906277A>G Locations: - p.Lys337Glu (Ensembl:ENSMUST00000030944) - c.1009A>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs240081623 | 342 | G>S | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.35) Somatic: No Accession: NC_000070.7:g.155906292G>A Codon: GGC/AGC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906292G>A Locations: - p.Gly342Ser (Ensembl:ENSMUST00000030944) - c.1024G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs253200711 | 344 | P>S | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.2) Somatic: No Accession: NC_000070.7:g.155906298C>T Codon: CCT/TCT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906298C>T Locations: - p.Pro344Ser (Ensembl:ENSMUST00000030944) - c.1030C>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs578612993 | 347 | P>L | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.38) Somatic: No Accession: NC_000070.7:g.155906308C>T Codon: CCC/CTC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906308C>T Locations: - p.Pro347Leu (Ensembl:ENSMUST00000030944) - c.1040C>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs582302641 | 348 | S>A | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.45) Somatic: No Accession: NC_000070.7:g.155906310T>G Codon: TCT/GCT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906310T>G Locations: - p.Ser348Ala (Ensembl:ENSMUST00000030944) - c.1042T>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs218327235 | 349 | G>V | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.88) Somatic: No Accession: NC_000070.7:g.155906314G>T Codon: GGA/GTA Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906314G>T Locations: - p.Gly349Val (Ensembl:ENSMUST00000030944) - c.1046G>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs235388091 | 351 | S>N | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: NC_000070.7:g.155906320G>A Codon: AGC/AAC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906320G>A Locations: - p.Ser351Asn (Ensembl:ENSMUST00000030944) - c.1052G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs217883236 | 363 | Q>K | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: NC_000070.7:g.155906355C>A Codon: CAG/AAG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906355C>A Locations: - p.Gln363Lys (Ensembl:ENSMUST00000030944) - c.1087C>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3543103513 | 364 | G>D | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.05) Somatic: No Accession: NC_000070.7:g.155906359G>A Codon: GGC/GAC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906359G>A Locations: - p.Gly364Asp (Ensembl:ENSMUST00000030944) - c.1091G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3543091607 | 365 | H>Y | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: NC_000070.7:g.155906361C>T Codon: CAC/TAC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906361C>T Locations: - p.His365Tyr (Ensembl:ENSMUST00000030944) - c.1093C>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs230581535 | 368 | V>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.24) Somatic: No Accession: NC_000070.7:g.155906370G>A Codon: GTA/ATA Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906370G>A Locations: - p.Val368Ile (Ensembl:ENSMUST00000030944) - c.1102G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388735304 | 376 | E>G | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.32) Somatic: No Accession: NC_000070.7:g.155906479A>G Codon: GAG/GGG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906479A>G Locations: - p.Glu376Gly (Ensembl:ENSMUST00000030944) - c.1127A>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388740676 | 385 | E>D | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: NC_000070.7:g.155906507G>C Codon: GAG/GAC Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155906507G>C Locations: - p.Glu385Asp (Ensembl:ENSMUST00000030944) - c.1155G>C (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388733143 | 425 | P>H | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: NC_000070.7:g.155907871C>A Codon: CCT/CAT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155907871C>A Locations: - p.Pro425His (Ensembl:ENSMUST00000030944) - c.1274C>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs254724008 | 472 | R>Q | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.03) Somatic: No Accession: NC_000070.7:g.155908012G>A Codon: CGA/CAA Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155908012G>A Locations: - p.Arg472Gln (Ensembl:ENSMUST00000030944) - c.1415G>A (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs33196386 | 477 | N>S | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.69) Somatic: No Accession: NC_000070.7:g.155908027A>G Codon: AAT/AGT Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155908027A>G Locations: - p.Asn477Ser (Ensembl:ENSMUST00000030944) - c.1430A>G (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3388729600 | 489 | R>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000070.7:g.155908063G>T Codon: AGA/ATA Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155908063G>T Locations: - p.Arg489Ile (Ensembl:ENSMUST00000030944) - c.1466G>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: | |||||||
rs3395201668 | 494 | E>V | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: NC_000070.7:g.155908078A>T Codon: GAG/GTG Consequence type: missense Cytogenetic band: 4q Genomic location: NC_000070.7:g.155908078A>T Locations: - p.Glu494Val (Ensembl:ENSMUST00000030944) - c.1481A>T (Ensembl:ENSMUST00000030944) Source type: large scale study Cross-references: |