Q9JJ80 · RPF2_MOUSE

  • Protein
    Ribosome production factor 2 homolog
  • Gene
    Rpf2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome
Cellular Componentnucleolus
Cellular Componentnucleoplasm
Molecular Function5S rRNA binding
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Biological Processmaturation of LSU-rRNA
Biological Processprotein localization to nucleolus
Biological Processregulation of signal transduction by p53 class mediator
Biological Processribosomal large subunit assembly
Biological Processribosomal large subunit biogenesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Ribosome production factor 2 homolog
  • Alternative names
    • Brix domain-containing protein 1
    • Ribosome biogenesis protein RPF2 homolog

Gene names

    • Name
      Rpf2
    • Synonyms
      Bxdc1
    • ORF names
      MNCb-4285

Organism names

  • Taxonomic identifier
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9JJ80
  • Secondary accessions
    • Q8R3K6
    • Q9CQ34
    • Q9CSY9
    • Q9CYR9

Proteomes

Organism-specific databases

Subcellular Location

Nucleus, nucleolus
Note: Associated with the nucleolus in an RNA-dependent manner.

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001202241-306Ribosome production factor 2 homolog

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain31-234Brix
Region270-306Disordered
Compositional bias272-300Basic and acidic residues

Sequence similarities

Belongs to the RPF2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    35,364
  • Last updated
    2001-09-26 v2
  • Checksum
    CF732DBD515794AB
MDALDKVLKPKTKRAKRFLEKREPKLTENIKNAMLIKGGNANATVTQVLRDMYALKKPYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEKFVSLKDIKTSKCPEGTKPMLIFAGDDFDVTEDFRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNGKVYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVMRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGTTFGRIHMQKQDLSKLQTRKMKGLKKRPAENGVDDQGKKSKRIKKN

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
S4R1Y5S4R1Y5_MOUSERpf2257
S4R2H5S4R2H5_MOUSERpf2205
S4R2R2S4R2R2_MOUSERpf2153
G3X926G3X926_MOUSERpf2273

Features

Showing features for sequence conflict, compositional bias.

TypeIDPosition(s)Description
Sequence conflict8in Ref. 1; BAA95117
Sequence conflict79in Ref. 2; BAB28829
Compositional bias272-300Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB041810
EMBL· GenBank· DDBJ
BAA95117.1
EMBL· GenBank· DDBJ
mRNA
AK010776
EMBL· GenBank· DDBJ
BAB27175.1
EMBL· GenBank· DDBJ
mRNA
AK011644
EMBL· GenBank· DDBJ
-mRNA No translation available.
AK012188
EMBL· GenBank· DDBJ
BAB28087.1
EMBL· GenBank· DDBJ
mRNA
AK012641
EMBL· GenBank· DDBJ
BAB28375.1
EMBL· GenBank· DDBJ
mRNA
AK013395
EMBL· GenBank· DDBJ
BAB28829.1
EMBL· GenBank· DDBJ
mRNA
AK017678
EMBL· GenBank· DDBJ
BAB30868.1
EMBL· GenBank· DDBJ
mRNA
AK020030
EMBL· GenBank· DDBJ
BAB31973.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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