Q9IB44 · Q9IB44_DANRE
- ProteinG2/mitotic-specific cyclin-B1
- Geneccnb1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids398 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | centrosome | |
Cellular Component | cyclin B1-CDK1 complex | |
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | cyclin-dependent protein serine/threonine kinase regulator activity | |
Biological Process | cell division | |
Biological Process | mitotic cell cycle phase transition | |
Biological Process | mitotic metaphase chromosome alignment | |
Biological Process | oocyte maturation |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameG2/mitotic-specific cyclin-B1
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ9IB44
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-25 | Disordered | ||||
Sequence: MMALRVTRNTRLASSENQNALPGKA | ||||||
Compositional bias | 8-22 | Polar residues | ||||
Sequence: RNTRLASSENQNALP | ||||||
Region | 76-101 | Disordered | ||||
Sequence: PKKDSPKVQHGVKVVSEPSSPVPMET | ||||||
Domain | 174-258 | Cyclin-like | ||||
Sequence: DWLVQVQIKFRLLQETMYMTVAIIDRFLQDHPVPKKQLQLVGVTAMFIASKYEEMYPPEIADFAFVTDRAYTTSQIREMEMKVLR | ||||||
Domain | 267-385 | Cyclin C-terminal | ||||
Sequence: PLPLQFLRRASKIGDVTAEHHTLAKYFLELTMVDYDMVHYPPSQMASAAYALTLKVFNCGDWTPTLQHYMGYTEDELVPVMQHIAKNVVRVNEGLSKHLAVKNKYSSQKQMRIATISQL | ||||||
Domain | 271-352 | Cyclin-like | ||||
Sequence: QFLRRASKIGDVTAEHHTLAKYFLELTMVDYDMVHYPPSQMASAAYALTLKVFNCGDWTPTLQHYMGYTEDELVPVMQHIAK |
Sequence similarities
Belongs to the cyclin family. Cyclin AB subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length398
- Mass (Da)44,836
- Last updated2000-10-01 v1
- Checksum8A26971453F5907A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 8-22 | Polar residues | ||||
Sequence: RNTRLASSENQNALP |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC153626 EMBL· GenBank· DDBJ | AAI53627.1 EMBL· GenBank· DDBJ | mRNA | ||
AF268043 EMBL· GenBank· DDBJ | AAP47013.1 EMBL· GenBank· DDBJ | mRNA | ||
AB040435 EMBL· GenBank· DDBJ | BAA92876.1 EMBL· GenBank· DDBJ | mRNA |