Q9HTZ7 · PCKA_PSEAE
- ProteinPhosphoenolpyruvate carboxykinase (ATP)
- GenepckA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids513 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
Catalytic activity
- oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2
Cofactor
Note: Binds 1 Mn2+ ion per subunit.
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 45 | substrate | |||
Binding site | 179 | substrate | |||
Binding site | 185 | ATP (UniProtKB | ChEBI) | |||
Binding site | 185 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 185 | substrate | |||
Binding site | 204 | ATP (UniProtKB | ChEBI) | |||
Binding site | 204 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 220-228 | ATP (UniProtKB | ChEBI) | |||
Binding site | 241 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 269 | ATP (UniProtKB | ChEBI) | |||
Binding site | 305 | ATP (UniProtKB | ChEBI) | |||
Binding site | 305 | substrate | |||
Binding site | 431 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoenolpyruvate carboxykinase (ATP) activity | |
Biological Process | gluconeogenesis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate carboxykinase (ATP)
- EC number
- Short namesPCK ; PEP carboxykinase ; PEPCK
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ9HTZ7
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000203833 | 1-513 | Phosphoenolpyruvate carboxykinase (ATP) | ||
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length513
- Mass (Da)55,732
- Last updated2001-03-01 v1
- Checksum4B2CD9794B3B3E1E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE004091 EMBL· GenBank· DDBJ | AAG08577.1 EMBL· GenBank· DDBJ | Genomic DNA |