Q9HP81 · HTR2_HALSA
- ProteinSensory rhodopsin II transducer
- Genehtr2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids764 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor. Responds to light changes through the variation of the level of methylation. Also acts as a chemotransducer.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | photoreceptor activity | |
Biological Process | chemotaxis | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSensory rhodopsin II transducer
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Halobacteriaceae > Halobacterium > Halobacterium salinarum NRC-34001
Accessions
- Primary accessionQ9HP81
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 2-16 | Cytoplasmic | ||||
Sequence: GSGLVARIRGSYGTK | ||||||
Transmembrane | 17-37 | Helical | ||||
Sequence: LTLALVVVVVLSVGVGTFVYQ | ||||||
Topological domain | 38-278 | Extracellular | ||||
Sequence: QTTTQLETDVRADLTGSADARADHLDAWLSNARGQTQLASRHPVLASGNDTAITRYLEGLAASDERPDGVVAAHVYNTSTTTIEASSADAFTGVNPREQGAPFATDPPSFATTSDVVVAAPFTVPAADFPVLSVLSPIPGTTDKALIYMVNVNTLTDDFGQNVAGSTTTVVSADGTYVSHPDQDRVLTGHDGPSRLLNQSRTQPAYIDANGTVTAAAPVDGAPWSVLVRAPHDRAFALGDF | ||||||
Transmembrane | 279-298 | Helical | ||||
Sequence: VASSLVGLVLITIVSLSLIG | ||||||
Topological domain | 299-764 | Cytoplasmic | ||||
Sequence: VTVGSTTVTALRQFSRRADEMAAGDLDTDIDTSRNDEFGTLAESFRSMRDSLSESLTDAERATARAEDAREDAEQQRADAEAAREDAEAARKDAQETARALESAAADYEEALTAVADGDLTRRVDASRDHDAMARIGHALNDMLDDIETSVAAATAFSDHVSDAAQRVEADAGDAIDAGTDVSTAVDEISDGATEQTDRLHEVAGEVDDLSASAEEVAETVASLADTAGQAASAVDDGRQATEDAVETMDDVADDAEAAADAMDALDSEMADIGEIVDVIADIADQTNMLALNASIEAARTGADGDGFAVVADEVKTLAEESRDAAEDIESRLLALQGQVSDVADEMRATSDTVSDGRATVGDAATALDDVVSFVADTDTAAGEIRAATDRQAHAASRVASAVDEVAGISQETAAQATAVADSAATQTDTLSSVDDAAADLADRAAALDDLLAEFDAHDDTEPEDY |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for initiator methionine, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M | ||||||
Chain | PRO_0000110549 | 2-764 | Sensory rhodopsin II transducer | |||
Sequence: GSGLVARIRGSYGTKLTLALVVVVVLSVGVGTFVYQQTTTQLETDVRADLTGSADARADHLDAWLSNARGQTQLASRHPVLASGNDTAITRYLEGLAASDERPDGVVAAHVYNTSTTTIEASSADAFTGVNPREQGAPFATDPPSFATTSDVVVAAPFTVPAADFPVLSVLSPIPGTTDKALIYMVNVNTLTDDFGQNVAGSTTTVVSADGTYVSHPDQDRVLTGHDGPSRLLNQSRTQPAYIDANGTVTAAAPVDGAPWSVLVRAPHDRAFALGDFVASSLVGLVLITIVSLSLIGVTVGSTTVTALRQFSRRADEMAAGDLDTDIDTSRNDEFGTLAESFRSMRDSLSESLTDAERATARAEDAREDAEQQRADAEAAREDAEAARKDAQETARALESAAADYEEALTAVADGDLTRRVDASRDHDAMARIGHALNDMLDDIETSVAAATAFSDHVSDAAQRVEADAGDAIDAGTDVSTAVDEISDGATEQTDRLHEVAGEVDDLSASAEEVAETVASLADTAGQAASAVDDGRQATEDAVETMDDVADDAEAAADAMDALDSEMADIGEIVDVIADIADQTNMLALNASIEAARTGADGDGFAVVADEVKTLAEESRDAAEDIESRLLALQGQVSDVADEMRATSDTVSDGRATVGDAATALDDVVSFVADTDTAAGEIRAATDRQAHAASRVASAVDEVAGISQETAAQATAVADSAATQTDTLSSVDDAAADLADRAAALDDLLAEFDAHDDTEPEDY |
Post-translational modification
Methylated by CheR.
Keywords
- PTM
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 303-355 | HAMP 1 | ||||
Sequence: STTVTALRQFSRRADEMAAGDLDTDIDTSRNDEFGTLAESFRSMRDSLSESLT | ||||||
Region | 347-401 | Disordered | ||||
Sequence: RDSLSESLTDAERATARAEDAREDAEQQRADAEAAREDAEAARKDAQETARALES | ||||||
Compositional bias | 351-396 | Basic and acidic residues | ||||
Sequence: SESLTDAERATARAEDAREDAEQQRADAEAAREDAEAARKDAQETA | ||||||
Domain | 397-450 | HAMP 2 | ||||
Sequence: RALESAAADYEEALTAVADGDLTRRVDASRDHDAMARIGHALNDMLDDIETSVA | ||||||
Domain | 469-705 | Methyl-accepting transducer | ||||
Sequence: DAGDAIDAGTDVSTAVDEISDGATEQTDRLHEVAGEVDDLSASAEEVAETVASLADTAGQAASAVDDGRQATEDAVETMDDVADDAEAAADAMDALDSEMADIGEIVDVIADIADQTNMLALNASIEAARTGADGDGFAVVADEVKTLAEESRDAAEDIESRLLALQGQVSDVADEMRATSDTVSDGRATVGDAATALDDVVSFVADTDTAAGEIRAATDRQAHAASRVASAVDEVA |
Sequence similarities
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length764
- Mass (Da)79,042
- Last updated2007-01-23 v2
- ChecksumD5EB26F706576996
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 107-110 | in Ref. 1; AAC44369 | ||||
Sequence: VVAA → RWFAG | ||||||
Compositional bias | 351-396 | Basic and acidic residues | ||||
Sequence: SESLTDAERATARAEDAREDAEQQRADAEAAREDAEAARKDAQETA | ||||||
Sequence conflict | 682 | in Ref. 1; AAC44369 | ||||
Sequence: E → Q |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U62676 EMBL· GenBank· DDBJ | AAC44369.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE004437 EMBL· GenBank· DDBJ | AAG19989.1 EMBL· GenBank· DDBJ | Genomic DNA |