Q9HNX6 · MPTA_HALSA

Function

function

Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion per subunit.

Pathway

Cofactor biosynthesis; 5,6,7,8-tetrahydromethanopterin biosynthesis.

Features

Showing features for site.

TypeIDPosition(s)Description
Site158May be catalytically important

GO annotations

AspectTerm
Molecular FunctionGTP cyclohydrolase activity
Molecular FunctionGTP cyclohydrolase I activity
Molecular FunctionGTP cyclohydrolase IV activity
Molecular Functioniron ion binding
Biological Processtetrahydromethanopterin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GTP cyclohydrolase MptA
  • EC number
  • Alternative names
    • GTP cyclohydrolase IV

Gene names

    • Name
      mptA
    • Ordered locus names
      VNG_1901C

Organism names

Accessions

  • Primary accession
    Q9HNX6

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001477411-311GTP cyclohydrolase MptA

Proteomic databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the GTP cyclohydrolase IV family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    311
  • Mass (Da)
    34,439
  • Last updated
    2001-03-01 v1
  • Checksum
    F1F4109854921078
MSQQLPDVQATEPDVSVGLSEVGVTGVEKLVEIAREDDRPIVLMAEFEVYVDLPRGRKGIDMSRNMRVIDETLEDAVREPIYRVEEMCGEVAERLLEKHDYTTTATVEMNAELMLREETPASDLPTQGTIDIIASATAQEDAPTREEIGARVVGMTVCPCSQQMMSETARRKLAELGVGEDAVREFLRDVPQAGHSQRGHATLTVEAGGDPDVNLMDLVSVARDSMSARIYNTAKRPDEDHMTYESHANAKFVEDCVRSMARGVVEEFDHLPEDAVVTMKQSNDESIHQHNAHAERVAEFGQLREEVGSGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE004437
EMBL· GenBank· DDBJ
AAG20094.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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