Q9HMK4 · SYFA_HALSA

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per tetramer.

Features

Showing features for binding site.

150250100150200250300350400450500
TypeIDPosition(s)Description
Binding site339L-phenylalanine (UniProtKB | ChEBI)
Binding site382-384L-phenylalanine (UniProtKB | ChEBI)
Binding site422L-phenylalanine (UniProtKB | ChEBI)
Binding site424Mg2+ (UniProtKB | ChEBI); shared with beta subunit
Binding site448L-phenylalanine (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Molecular Functionphenylalanine-tRNA ligase activity
Molecular FunctiontRNA binding
Biological Processphenylalanyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phenylalanine--tRNA ligase alpha subunit
  • EC number
  • Alternative names
    • Phenylalanyl-tRNA synthetase alpha subunit
      (PheRS
      )

Gene names

    • Name
      pheS
    • Ordered locus names
      VNG_2504G

Organism names

Accessions

  • Primary accession
    Q9HMK4

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001268081-502Phenylalanine--tRNA ligase alpha subunit

Proteomic databases

Interaction

Subunit

Tetramer of two alpha and two beta subunits.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    502
  • Mass (Da)
    54,332
  • Last updated
    2001-03-01 v1
  • Checksum
    8B2FCCDD01E5528C
MQLPTQQVAVLDAASTDDPQRIEALAADTDYPPETIAGAALALEAEGLVAVTETTTTTVSLTDEGHAYATDGLPEVRLYRAALDAGADDAPVEMGSVIGAAGLDGPQVDIALSNYARKGYGTIDSGALAADPDADPENDPEADALATLTDGDSVDDDAVVDQLASRDLVTVSERTVRSVTLTEAGVTELMAGVEATDEVGELTPELLASGEWADVEFADYNVAADAADHTPGKTHVLRQAAERVTDVLVGMGFQEMAGPHVDADFYINDCLFMPQDHPARNHWDRFALSNPARIDELPDALVERVERAHREGAGDDGDGYHSPWDEDFARALALRGHTTSLTARHLAGLADADVEAPARYFSVEKAYRNDTLDATHLLEFFQIEGWVLADDLSVRDLMGTFREFYSQFGIHDLQFKPTYNPYTEPSFELFGRHPETGELIEIGNSGIFRPEMLDPLDVDGDVMAWGLALERLLMLMTGFEDIRDVHGTLCDVGFLRNAEVVY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE004437
EMBL· GenBank· DDBJ
AAG20567.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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