Q9HHH8 · TF2B5_HALSA

Function

function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

Features

Showing features for binding site.

130720406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site23Zn2+ (UniProtKB | ChEBI)
Binding site26Zn2+ (UniProtKB | ChEBI)
Binding site39Zn2+ (UniProtKB | ChEBI)
Binding site42Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenttranscription preinitiation complex
Molecular FunctionDNA-binding transcription factor activity
Molecular FunctionTBP-class protein binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription initiation
Biological Processtranscription preinitiation complex assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription initiation factor IIB 5
  • Short names
    TFIIB 5

Gene names

    • Name
      tfbE
    • Ordered locus names
      VNG_6389G

Encoded on

  • Plasmid pNRC200

Organism names

Accessions

  • Primary accession
    Q9HHH8

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001193151-307Transcription initiation factor IIB 5

Structure

Family & Domains

Features

Showing features for zinc finger, region, compositional bias, repeat.

Type
IDPosition(s)Description
Zinc finger19-47TFIIB-type
Region54-121Disordered
Compositional bias95-121Basic and acidic residues
Repeat129-2121
Repeat223-3042

Sequence similarities

Belongs to the TFIIB family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    307
  • Mass (Da)
    33,264
  • Last updated
    2001-03-01 v1
  • Checksum
    F4C767B22EAFC1A1
MTTSEPYERAFDEDIQRGTTEPCPECGGPVRTNSAETVCADCGLIIDEQSIDRGPEWHRDDADTAKRTGAPLTPARHDRGLSTVIGSGQDARGTALSSEKRRRLARMRREQSRGRWRSTKERNLGHGLTEIRRIASALGLADSVRDQACQLFRTAQNERLLKGRSIEAMAAASVFGACRCNGESWLIDDVAPMAQVGQNRVENAYTVLNEELGLPTPPVSLDQFVPRLASDLGCTDVVRRRAEELVVQAVDAGITTGVHPSGFAAACLYMAACVHDAPLTQADAAAAAGVTVETIRSHRDRLLSIVE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias95-121Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE004438
EMBL· GenBank· DDBJ
AAG21002.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp