Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueColonCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 36:40-45 (2004)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueOvary, RetinoblastomaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.Foxler D.E., Bridge K.S., James V., Webb T.M., Mee M., Wong S.C., Feng Y., Constantin-Teodosiu D., Petursdottir T.E.[...], Sharp T.V.View abstractCited forINTERACTION WITH LIMD1; WTIP AND AJUBACategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Cell Biol. 14:201-208 (2012)Cited in10Mapped to40
Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.Henze A.T., Garvalov B.K., Seidel S., Cuesta A.M., Ritter M., Filatova A., Foss F., Dopeso H., Essmann C.L.[...], Acker T.View abstractAnnotationPHD3 loss sustains cell proliferation through the control of EGFR.CategoriesFunctionSourceGeneRif: 112399PubMedEurope PMCNat Commun 5:5582-5582 (2014)Mapped to59
A proteome-scale map of the human interactome network.Rolland T., Tasan M., Charloteaux B., Pevzner S.J., Zhong Q., Sahni N., Yi S., Lemmens I., Fontanillo C.[...], Vidal M.View abstractCategoriesInteractionSourceIntAct: Q9H6Z9PubMedEurope PMCCell 159:1212-1226 (2014)Mapped to99+
Toward an understanding of the protein interaction network of the human liver.Wang J., Huo K., Ma L., Tang L., Li D., Huang X., Yuan Y., Li C., Wang W.[...], Yang X.View abstractCategoriesInteractionSourceIntAct: Q9H6Z9PubMedEurope PMCMol Syst Biol 7:536-536 (2011)Mapped to99+
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.Rose J.E., Behm F.M., Drgon T., Johnson C., Uhl G.R.View abstractAnnotationClinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)CategoriesFunctionSourceGeneRif: 112399PubMedEurope PMCMol Med 16:247-253 (2010)Mapped to99+
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.Maynard M.A., Qi H., Chung J., Lee E.H., Kondo Y., Hara S., Conaway R.C., Conaway J.W., Ohh M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1234104, Reactome: R-HSA-1234115PubMedEurope PMCJ. Biol. Chem. 278:11032-11040 (2003)Cited in1Mapped to54
Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein.Groulx I., Lee S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1234115PubMedEurope PMCMol Cell Biol 22:5319-5336 (2002)Mapped to82
Hypoxia-inducible factor-1 alpha (HIF-1 alpha) escapes O(2)-driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm.Berra E., Roux D., Richard D.E., Pouyssegur J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1234115PubMedEurope PMCEMBO Rep 2:615-620 (2001)Mapped to81
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.Ivan M., Kondo K., Yang H., Kim W., Valiando J., Ohh M., Salic A., Asara J.M., Lane W.S., Kaelin W.G. Jr.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1234104, Reactome: R-HSA-1234115PubMedEurope PMCScience 292:464-468 (2001)Mapped to83
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.Jaakkola P., Mole D.R., Tian Y.-M., Wilson M.I., Gielbert J., Gaskell S.J., von Kriegsheim A., Hebestreit H.F., Mukherji M.[...], Ratcliffe P.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1234104, Reactome: R-HSA-1234115PubMedEurope PMCScience 292:468-472 (2001)Cited in1Mapped to77