A novel BAP28 gene and protein.Bougueleret L., Chumakov I., Barry C., Cohen-Akenine A.Cited forNUCLEOTIDE SEQUENCE [MRNA], VARIANTS ARG-348; VAL-607; SER-1694; ALA-1854; ASP-1967 AND GLY-2017CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Patent Patent publication WO0100669 (04-JAN-2001)Cited in1
Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells.Prieto J.L., McStay B.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, SUBUNITCategoriesFunction, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenes Dev. 21:2041-2054 (2007)Cited in5Mapped to8
Detection and validation of non-synonymous coding SNPs from orthogonal analysis of shotgun proteomics data.Bunger M.K., Cargile B.J., Sevinsky J.R., Deyanova E., Yates N.A., Hendrickson R.C., Stephenson J.L. Jr.View abstractCited forVARIANT GLY-2017, IDENTIFICATION BY MASS SPECTROMETRYCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Proteome Res. 6:2331-2340 (2007)Cited in7
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.Yang X.M., Wang X.Q., Hu L.P., Feng M.X., Zhou Y.Q., Li D.X., Li J., Miao X.C., Zhang Y.L.[...], Zhang Z.G.View abstractAnnotationNucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.SourceGeneRif: 55127PubMedEurope PMCGastroenterology 165:629-646 (2023)Mapped to9
HEATR1, a novel interactor of Pontin/Reptin, stabilizes Pontin/Reptin and promotes cell proliferation of oral squamous cell carcinoma.Nakamura A., Kakihara Y., Funayama A., Haga K., Mikami T., Kobayashi D., Yoshida Y., Izumi K., Kobayashi T., Saeki M.View abstractAnnotationHEATR1 a novel interactor of Pontin/Reptin stabilizes Pontin/Reptin and promotes cell proliferation of oral squamous cell carcinoma.CategoriesInteractionSourceGeneRif: 55127PubMedEurope PMCBiochem Biophys Res Commun 557:294-301 (2021)Mapped to20
HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.Zhao J., Zhu Y., Fu Q., Zhu Y., Zhao G.View abstractAnnotationHEATR1 promotes proliferation in gastric cancer in vitro and in vivo.CategoriesFunction, ExpressionSourceGeneRif: 55127PubMedEurope PMCActa Biochim Biophys Sin (Shanghai) 52:1030-1039 (2020)Mapped to9
HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling.Zhou Y., Wang K., Zhou Y., Li T., Yang M., Wang R., Chen Y., Cao M., Hu R.View abstractAnnotationHEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling.CategoriesFunction, InteractionSourceGeneRif: 55127PubMedEurope PMCRedox Biol 29:101390-101390 (2020)Mapped to16
Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.Turi Z., Senkyrikova M., Mistrik M., Bartek J., Moudry P.View abstractAnnotationThese findings reveal an important role for HEATR1 in ribosome biogenesis.CategoriesFunctionSourceGeneRif: 55127PubMedEurope PMCCell Cycle 17:92-101 (2018)Mapped to9
Glioma-associated antigen HEATR1 induces functional cytotoxic T lymphocytes in patients with glioma.Wu Z.B., Qiu C., Zhang A.L., Cai L., Lin S.J., Yao Y., Tang Q.S., Xu M., Hua W.[...], Zhou L.F.View abstractAnnotationGlioma-associated antigen HEATR1 induces functional cytotoxic T lymphocytes in patients with glioma.CategoriesExpressionSourceGeneRif: 55127PubMedEurope PMCJ Immunol Res 2014:131494-131494 (2014)Mapped to9
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.Thomas S.R., Keller C.A., Szyk A., Cannon J.R., Laronde-Leblanc N.A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-6790721PubMedEurope PMCNucleic Acids Res. 39:2445-2457 (2011)Cited in2Mapped to48
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Psi1191 in yeast 18S rRNA.Meyer B., Wurm J.P., Kotter P., Leisegang M.S., Schilling V., Buchhaupt M., Held M., Bahr U., Karas M.[...], Entian K.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-6790721PubMedEurope PMCNucleic Acids Res. 39:1526-1537 (2011)Cited in1Mapped to48
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase.Wurm J.P., Meyer B., Bahr U., Held M., Frolow O., Kotter P., Engels J.W., Heckel A., Karas M.[...], Wohnert J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-6790721PubMedEurope PMCNucleic Acids Res. 38:2387-2398 (2010)Cited in2Mapped to47