Q9H339 · O51B5_HUMAN
- ProteinOlfactory receptor 51B5
- GeneOR51B5
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids312 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Odorant receptor.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Molecular Function | G protein-coupled receptor activity | |
Molecular Function | olfactory receptor activity | |
Biological Process | sensory perception of smell |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOlfactory receptor 51B5
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ9H339
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-23 | Extracellular | ||||
Sequence: MSSSGSSHPFLLTGFPGLEEAHH | ||||||
Transmembrane | 24-44 | Helical; Name=1 | ||||
Sequence: WISVFFLFMYISILFGNGTLL | ||||||
Topological domain | 45-52 | Cytoplasmic | ||||
Sequence: LLIKEDHN | ||||||
Transmembrane | 53-73 | Helical; Name=2 | ||||
Sequence: LHEPMYFFLAMLAATDLGLAL | ||||||
Topological domain | 74-97 | Extracellular | ||||
Sequence: TTMPTVLGVLWLDHREIGSAACFS | ||||||
Transmembrane | 98-118 | Helical; Name=3 | ||||
Sequence: QAYFIHSLSFLESGILLAMAY | ||||||
Topological domain | 119-137 | Cytoplasmic | ||||
Sequence: DRFIAICNPLRYTSVLTNT | ||||||
Transmembrane | 138-158 | Helical; Name=4 | ||||
Sequence: RVVKIGLGVLMRGFVSVVPPI | ||||||
Topological domain | 159-194 | Extracellular | ||||
Sequence: RPLYFFLYCHSHVLSHAFCLHQDVIKLACADTTFNR | ||||||
Transmembrane | 195-215 | Helical; Name=5 | ||||
Sequence: LYPAVLVVFIFVLDYLIIFIS | ||||||
Topological domain | 216-235 | Cytoplasmic | ||||
Sequence: YVLILKTVLSIASREERAKA | ||||||
Transmembrane | 236-256 | Helical; Name=6 | ||||
Sequence: LITCVSHICCVLVFYVTVIGL | ||||||
Topological domain | 257-271 | Extracellular | ||||
Sequence: SLIHRFGKQVPHIVH | ||||||
Transmembrane | 272-292 | Helical; Name=7 | ||||
Sequence: LIMSYAYFLFPPLMNPITYSV | ||||||
Topological domain | 293-312 | Cytoplasmic | ||||
Sequence: KTKQIQNAILHLFTTHRIGT |
Keywords
- Cellular component
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_053307 | 5 | in dbSNP:rs11036913 | |||
Sequence: G → S | ||||||
Natural variant | VAR_062078 | 78 | in dbSNP:rs57273781 | |||
Sequence: T → K | ||||||
Natural variant | VAR_062079 | 88 | in dbSNP:rs57900141 | |||
Sequence: R → G | ||||||
Natural variant | VAR_053308 | 102 | in dbSNP:rs11036912 | |||
Sequence: I → T | ||||||
Natural variant | VAR_053309 | 154 | in dbSNP:rs12273630 | |||
Sequence: V → I | ||||||
Natural variant | VAR_053310 | 160 | in dbSNP:rs4910551 | |||
Sequence: P → L | ||||||
Natural variant | VAR_053311 | 220 | in dbSNP:rs7120319 | |||
Sequence: L → F |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 505 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000150747 | 1-312 | Olfactory receptor 51B5 | |||
Sequence: MSSSGSSHPFLLTGFPGLEEAHHWISVFFLFMYISILFGNGTLLLLIKEDHNLHEPMYFFLAMLAATDLGLALTTMPTVLGVLWLDHREIGSAACFSQAYFIHSLSFLESGILLAMAYDRFIAICNPLRYTSVLTNTRVVKIGLGVLMRGFVSVVPPIRPLYFFLYCHSHVLSHAFCLHQDVIKLACADTTFNRLYPAVLVVFIFVLDYLIIFISYVLILKTVLSIASREERAKALITCVSHICCVLVFYVTVIGLSLIHRFGKQVPHIVHLIMSYAYFLFPPLMNPITYSVKTKQIQNAILHLFTTHRIGT | ||||||
Disulfide bond | 95↔187 | |||||
Sequence: CFSQAYFIHSLSFLESGILLAMAYDRFIAICNPLRYTSVLTNTRVVKIGLGVLMRGFVSVVPPIRPLYFFLYCHSHVLSHAFCLHQDVIKLAC |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length312
- Mass (Da)35,241
- Last updated2010-05-18 v2
- ChecksumCC84A55EDED229C4
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2R8Y7B5 | A0A2R8Y7B5_HUMAN | OR51B5 | 194 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF137396 EMBL· GenBank· DDBJ | AAG41683.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AC104389 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CH471064 EMBL· GenBank· DDBJ | EAW68799.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC136707 EMBL· GenBank· DDBJ | AAI36708.1 EMBL· GenBank· DDBJ | mRNA | ||
BC136708 EMBL· GenBank· DDBJ | AAI36709.1 EMBL· GenBank· DDBJ | mRNA | ||
BK004430 EMBL· GenBank· DDBJ | DAA04828.1 EMBL· GenBank· DDBJ | Genomic DNA |