Q9H320 · VCX1_HUMAN

  • Protein
    Variable charge X-linked protein 1
  • Gene
    VCX
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

May mediate a process in spermatogenesis or may play a role in sex ratio distortion.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleolus
Cellular Componentnucleus
Molecular Functionchromatin binding
Biological Processbrain development
Biological Processchromatin organization
Biological Processribosome assembly
Biological Processspermatogenesis

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Variable charge X-linked protein 1
  • Alternative names
    • Variable charge protein on X with ten repeats (VCX-10r)
    • Variably charged protein X-B1 (VCX-B1)

Gene names

    • Name
      VCX
    • Synonyms
      VCX1, VCX10R, VCXB1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q9H320
  • Secondary accessions
    • A0JNS5
    • Q4V774
    • Q9P0H3

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variantVAR_07043170in dbSNP:rs6639946
Natural variantVAR_070432194in dbSNP:rs78342118

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 478 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001846591-206Variable charge X-linked protein 1

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed exclusively in testis.

Gene expression databases

Organism-specific databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias, repeat.

TypeIDPosition(s)Description
Region1-206Disordered
Compositional bias18-32Polar residues
Compositional bias36-54Basic residues
Repeat104-1131
Region104-20310 X 10 AA tandem repeats of L-S-Q-E-S-[EQ]-V-E-E-P
Repeat114-1232
Compositional bias119-193Polar residues
Repeat124-1333
Repeat134-1434
Repeat144-1535
Repeat154-1636
Repeat164-1737
Repeat174-1838
Repeat184-1939
Repeat194-20310

Sequence similarities

Belongs to the VCX/VCY family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    206
  • Mass (Da)
    22,289
  • Last updated
    2001-03-01 v1
  • Checksum
    070880B5587C2BB0
MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPSV

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
J3KNW2J3KNW2_HUMANVCX186
A0A8I5QKN2A0A8I5QKN2_HUMANVCX166
A0A087X1S4A0A087X1S4_HUMANVCX186

Features

Showing features for sequence conflict, compositional bias.

TypeIDPosition(s)Description
Sequence conflict15-17in Ref. 3; AAH98123
Compositional bias18-32Polar residues
Compositional bias36-54Basic residues
Sequence conflict108in Ref. 3; AAH98123
Compositional bias119-193Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF167081
EMBL· GenBank· DDBJ
AAG41767.1
EMBL· GenBank· DDBJ
mRNA
AF159129
EMBL· GenBank· DDBJ
AAF28174.1
EMBL· GenBank· DDBJ
mRNA
BC098123
EMBL· GenBank· DDBJ
AAH98123.1
EMBL· GenBank· DDBJ
mRNA
BC126903
EMBL· GenBank· DDBJ
AAI26904.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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