Q9GYZ0 · KIF15_STRPU

Function

function

Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly. Plays a role in positioning spindle poles during mitosis, specifically at prometaphase.

Features

Showing features for binding site.

114632004006008001,0001,2001,400
TypeIDPosition(s)Description
Binding site99-106ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentkinesin complex
Cellular Componentmicrotubule
Cellular Componentspindle pole
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionmicrotubule binding
Molecular Functionmicrotubule motor activity
Molecular Functionplus-end-directed microtubule motor activity
Biological Processcentrosome separation
Biological Processmicrotubule-based movement
Biological Processmitotic spindle assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Kinesin-like protein KIF15
  • Alternative names
    • Kinesin-related protein KRP180

Gene names

    • Name
      KIF15

Organism names

Accessions

  • Primary accession
    Q9GYZ0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003286871-1463Kinesin-like protein KIF15

Expression

Developmental stage

Expressed in eggs.

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Domain18-354Kinesin motor
Region387-424Disordered
Compositional bias395-424Polar residues
Coiled coil436-517
Coiled coil586-646
Region686-720Disordered
Compositional bias703-720Polar residues
Region1335-1356Disordered
Compositional bias1409-1428Basic and acidic residues
Region1409-1444Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,463
  • Mass (Da)
    166,590
  • Last updated
    2001-03-01 v1
  • Checksum
    1E8BFC2BB5AEF94D
MSKKLKEQAANDASEGDAIKVFVRVRPSESHDADAAFGQCLEVRLPDTIIMHSKPEPKVFTYDHVTAANTTQESVFTAVGKRIIESCVGGFNGTIFAYGQTGSGKTFTMLGPCEDGDNFHHEMRGVIPRSFEYLFSLVNREREKHGDRYEFLCRCSFLEIYNEQIYDLLDPASLGLHLRENMKKGVFVDGLIERAVASASEAYGVLQAGWHNRRVAATSMNRESSRSHAVFTVSIESKEKKAGVSNIRVSQLHLVDLAGSERQKDTKAIGVRLKEAGSINKSLSILGNVIMALVDIAHGKQRHVPYRDSKLSFLLRDSLGGNAKTYIIANVHPDAKCFGETLSTLKFARRAKMIKNRAVVNEDTQGNVMHLQAEIRRLREALCMKGAEGSIPRGPSESGDSQMSNSSTESNGPVSGQQSGSSSSSKWKKYFLEAMSLRDIVEVEKREMREKVSSLEELCSKRDQVISSNKMIIKFRNSTIDMLQKTKNKALLKEDRDLLNENLKKEIEQLQEQLEHNPFVMRYVVENQSLRAQNKKLKMMEAVRSGEAMAATKAEELETLFLELREGLSKNRRYSSTPVDGEKVPTSTLVILKSQIKKLQDELENAKQEHAEQEEMTRTTRLDLESELAAYKKANLDMEKTLQGMKIKNRMDRDAMNDIHMQTIKSITTPKKVTYQLRSRTVLRTAGEETPGGPGFAGLSDNGSPLRSHSTNSLPPSGDILVTNSSPAMSEEGIIDEEMPEHVIEQCNEALTIELQKLQDKNANLQQQLEEHESQKHKMLQNSSKLDHQLQQITELYSTESQAWQEHEKDLTTRLAEATIQISTLQRDYEMTRGEAEDFKVMLQAADKEIGQEKKQKSKVTQDWDRVRAALDAQVVRLENEMCGQSRELENLTEDREQLQDAYNTLQAEHEFQQQREADLENRLKGKKAEITQLQEEIQKHLEKLDSERDKSMRLTAELRQGDNTKKDLLDAQELIDQFREERDDLLHRLDTEALKLSSSKEDLETVNSALTAIKKTDVEQKEALSSLMAALQGQKGMVKDKEEQLASMQMQLEDTRGQVSLLEAALEEGKASGAGLQSQIAALEDRMHAQAGEYQEQIEQMRADAMDANQHQKELLKELEKQSEELTQLHKQMKEKEEEYETKESEHKDTIESLEEQLEEVKTNLSTVVVELDEPESKKRKMADAQAMEIESLRDSEKRFKELSSVYDNMRDQMNEEIRSLKMKADELEDVRISKEILQAQHTALTYEIEQVRNEMAEKESSLKDEVNHLKRDMERQKTVLASMLRDKDEAVEKLYTVQTTLDQVKANEEILQENMDQVMEELDRTSALESTHFKEKEDIKSKLEEEREEKSKLTKDLTRLKEVYEEAEKKITELGGHQNPKQKIHHLQAVKSENYFLKEEVESLEKQLGKAQSDSEQMKRDYEALQKRLTSSSAEPPEEAGATTCIRCLPHSKRIMQTQTA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias395-424Polar residues
Compositional bias703-720Polar residues
Compositional bias1409-1428Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF284333
EMBL· GenBank· DDBJ
AAG01844.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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