Q9FZ97 · MUC70_ARATH

Function

function

Probable glycosyltransferase involved in pectin and/or xylans biosynthesis in cell walls (By similarity).
Together with IRX14, required for xylan and pectin synthesis in seed coat epidermal (SCE) cells (PubMed:30228108).
Collaboratively with GAUT11, essential for the accumulation of seed mucilage, a gelatinous wall rich in unbranched rhamnogalacturonan I (RG I), and for shaping the surface morphology of seeds (PubMed:30228108).

Pathway

Glycan metabolism; pectin biosynthesis.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi membrane
Molecular Functionglycosyltransferase activity
Biological Processmucilage extrusion from seed coat
Biological Processmucilage pectin biosynthetic process
Biological Processrhamnogalacturonan I biosynthetic process
Biological Processxylan metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable hexosyltransferase MUCI70
  • EC number
  • Alternative names
    • Protein MUCILAGE-RELATED 70

Gene names

    • Name
      MUCI70
    • ORF names
      F3H9.11
    • Ordered locus names
      At1g28240

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9FZ97
  • Secondary accessions
    • Q8W4K7

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Golgi apparatus membrane
; Single-pass type II membrane protein

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-58Cytoplasmic
Transmembrane59-79Helical; Signal-anchor for type II membrane protein
Topological domain80-581Lumenal

Keywords

Phenotypes & Variants

Disruption phenotype

Strong reduction of seed mucilage accumulation and major decrease in rhamnogalacturonan I (RG I), associated with reduced absolute levels of rhamnose (Rha), arabinose (Ara) and galacturonic acid (GalA) but increased absolute abundance of minor sugars (e.g. galactose (Gal), xylose (Xyl), glucose (Glc) and mannose (Man)) (PubMed:30228108).
The double mutant muci70-1 gaut11-3 is completely defective in seed mucilage production and exhibits a strong release of minor sugars in total mucilage extracts (PubMed:30228108).
Plants missing both MUCI70 and IRX14 exhibit a severe reduction in both xylan- and pectin-related sugars in total seed mucilage extracts (PubMed:30228108).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 31 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, glycosylation.

Type
IDPosition(s)Description
ChainPRO_00004507581-581Probable hexosyltransferase MUCI70
Glycosylation96N-linked (GlcNAc...) asparagine
Glycosylation102N-linked (GlcNAc...) asparagine
Glycosylation119N-linked (GlcNAc...) asparagine
Glycosylation194N-linked (GlcNAc...) asparagine
Glycosylation224N-linked (GlcNAc...) asparagine
Glycosylation285N-linked (GlcNAc...) asparagine
Glycosylation382N-linked (GlcNAc...) asparagine
Glycosylation411N-linked (GlcNAc...) asparagine
Glycosylation488N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in siliques and seeds.

Developmental stage

Accumulates in developing seeds in siliques, mainly in the seed coat and, to a lesser extent, in the embryo.

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region514-581Disordered
Compositional bias520-539Pro residues
Compositional bias550-569Basic residues

Sequence similarities

Belongs to the glycosyltransferase 8 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    581
  • Mass (Da)
    65,578
  • Last updated
    2001-03-01 v1
  • Checksum
    78E72252332F91AC
MTGLGVRSSSYGSLEKTGLNGVVLPIQITTTTRTKPSKMQKDREGIVHWICKFAGRKKVGMLLLFLISAVVFLRVLYVGKGEDSQEGQGPPSLHFNGSSGVNYSNMLQTNEELNMNIGNISFKAKEVIVFPPPPIHFLGYSLPQGHPCNSFTLPPPPADRKRTGPRPCPVCYLPVEEAVALMPNAPSFSPVLKNLTYIYEEPLNRETEFGGSDFGGYPTLKHRNDSFDIKETMSVHCGFVKGPQPGRNTGFDIDEADLLEMKQCRGIVVASAVFDAFDDVKAPQNISKYAEETVCFYMFVDEETESILKRERGLDGNKKVGIWRVVVVHNLPYSDGRRNGKVPKLLVHRMFPNARYSLWIDGKLELVVDPYQILERFLWRKNATFAISRHYKRFDVLVEAEANKAAGKYDNASIDFQVDFYKNEGLTPYSVAKLPITSDVPEGCVILREHVPISNLFTCLWFNEVDRFTSRDQISFSTVRDKIAAKTNWTVSMFLDCERRNFVVQRYHRAEQERFARQRPPVPNFPPPPPSPPPPVLISSDLPRKMSSGRATPPRRRGRDRRSGQRGHRKANLPVRLPDSA

Features

Showing features for sequence conflict, compositional bias.

Type
IDPosition(s)Description
Sequence conflict177in Ref. 1; ARJ31408 and 4; AAL32582/AAN72102
Compositional bias520-539Pro residues
Compositional bias550-569Basic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KY906044
EMBL· GenBank· DDBJ
ARJ31408.1
EMBL· GenBank· DDBJ
mRNA
AC021044
EMBL· GenBank· DDBJ
AAF98431.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE30935.1
EMBL· GenBank· DDBJ
Genomic DNA
AY062504
EMBL· GenBank· DDBJ
AAL32582.1
EMBL· GenBank· DDBJ
mRNA
BT002091
EMBL· GenBank· DDBJ
AAN72102.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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