Q9FYL8 · NFD2_ARATH
- ProteinProtein NUCLEAR FUSION DEFECTIVE 2
- GeneNFD2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids191 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Cellular Component | plant-type vacuole | |
Molecular Function | ribonuclease III activity | |
Biological Process | karyogamy | |
Biological Process | polar nucleus fusion | |
Biological Process | RNA processing |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProtein NUCLEAR FUSION DEFECTIVE 2
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FYL8
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Phenotypes & Variants
Disruption phenotype
Failure of fusion of the polar nuclei during megagametogenesis.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 23 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-29 | |||||
Sequence: MATLRFTLLLLVFVVGIFFSFSSVSHVRA | ||||||
Chain | PRO_0000431841 | 30-191 | Protein NUCLEAR FUSION DEFECTIVE 2 | |||
Sequence: TSEINLRIEPFSSPFATDLAKLQTQIGYKFNNINLLRRAMTHASFSQENNKALSIFGTHIIETAVSLQFLAKDIDISSKALGRLISEVSNVESSCALDGDRLGLGKIIRVSTKTDASNSAILCTGFRAIFGAIAIDAGTVDEAIKVFWKVHGARAGRLVSML |
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 48-167 | RNase III | ||||
Sequence: LAKLQTQIGYKFNNINLLRRAMTHASFSQENNKALSIFGTHIIETAVSLQFLAKDIDISSKALGRLISEVSNVESSCALDGDRLGLGKIIRVSTKTDASNSAILCTGFRAIFGAIAIDAG |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length191
- Mass (Da)20,742
- Last updated2001-03-01 v1
- Checksum3B3182038836B9FC
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC000103 EMBL· GenBank· DDBJ | AAF97957.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE30531.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY045598 EMBL· GenBank· DDBJ | AAK73956.1 EMBL· GenBank· DDBJ | mRNA | ||
AY094027 EMBL· GenBank· DDBJ | AAM16183.1 EMBL· GenBank· DDBJ | mRNA |