Q9FVZ0 · Q9FVZ0_ORYSJ

Function

function

Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

Catalytic activity

Cofactor

a monovalent cation (UniProtKB | Rhea| CHEBI:60242 )

Note: A monovalent cation.

Pathway

Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site152Mg2+ 1 (UniProtKB | ChEBI)
Binding site221Mg2+ 1 (UniProtKB | ChEBI)
Binding site249Mg2+ 1 (UniProtKB | ChEBI)
Binding site350ATP (UniProtKB | ChEBI)
Binding site372ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functiontetrahydrofolylpolyglutamate synthase activity
Biological Processone-carbon metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Folylpolyglutamate synthase
  • EC number
  • Alternative names
    • Folylpoly-gamma-glutamate synthetase
    • Tetrahydrofolylpolyglutamate synthase

Gene names

    • Name
      OSJNBb0073N24.10

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q9FVZ0

Proteomes

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region23-47Disordered

Sequence similarities

Belongs to the folylpolyglutamate synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    546
  • Mass (Da)
    60,109
  • Last updated
    2001-03-01 v1
  • Checksum
    673296EE35FA5464
MPPPRLAHLRRRSSSLLLLHHNHHHHRGGGSAPPHPLLRPPPPPQSHPFQLLTPRAAMASVAQPGVAAGSAEYEEVLGCISSLITQKVRADTGNRGNQWELMAKYLQILELEEPIARLKVVHVAGTKGKGSTCTFAESILRSCGFRTGLFTSPHLMDVRERFRLNGLDISEEKFIRYFWWCWNKLKDKTGGDIPMPAYFRFLALLAFKIFSDEQVDVAVLEVGLGGKYDATNVVKAPVVCGISSLGYDHMEILGNTLGEIAGEKAGILKKGVPAYTVPQPEEAMSVLKHRASELGVPLQVVQPLDPQQLDDQPLGLHGEHQYMNAGLAVALVTLPDQFIEGLSSACLQGRAQIVPDPEVLSKDSSSLIFYLDGAHSPESMEICAKWFSCVTRKDEQQPGPLDQLHIGTNSRKILLFNCMSVRDPQRLLPCLLATCAQNGLQFDHALFVPNQSQYNKLGSHASPPSERVQIDLSWQLSLQRVWEGLLHSNKGLNGSNSSTASSVFESLPLAIKWLRETAQQNQSTSYQVLVTGSLHLVGDVLRLLKE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC078840
EMBL· GenBank· DDBJ
AAG13624.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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