Q9FLT5 · AB9A_ARATH
- ProteinABC transporter A family member 9
- GeneABCA9
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids950 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Mediates the transport of acyl-CoAs and/or free fatty acids to the endoplasmic reticulum. Has no effect on the selectivity of fatty acid incorporation into triacylglycerol or further desaturation steps.
Biotechnology
Overexpression of ABCA9 increases seed oil content.
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | intracellular membrane-bounded organelle | |
Molecular Function | ABC-type transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATPase-coupled transmembrane transporter activity | |
Molecular Function | fatty acid transmembrane transporter activity | |
Molecular Function | lipid transporter activity | |
Biological Process | lipid transport | |
Biological Process | seed development |
Keywords
- Biological process
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameABC transporter A family member 9
- Short namesABC transporter ABCA.9; AtABCA9
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FLT5
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 31-51 | Helical | ||||
Sequence: ATCLHLFSSFFFILLIFSIEE | ||||||
Transmembrane | 223-243 | Helical | ||||
Sequence: IISAFYLMGPVFFLAFSMFGF | ||||||
Transmembrane | 276-296 | Helical | ||||
Sequence: WLIWEGILTFVSSLFLVLFGM | ||||||
Transmembrane | 308-328 | Helical | ||||
Sequence: FVLVFLLFFLFQFNMIGLAFA | ||||||
Transmembrane | 342-362 | Helical | ||||
Sequence: VGFLVFLVGFITQIVTTAGFP | ||||||
Transmembrane | 426-446 | Helical | ||||
Sequence: IWLVGTFFFWFVLALYFDNII |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Reduced seed size with abnormal morphology and reduced triacylglycerol content. Retarded growth on medium lacking sucrose.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 77 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000240330 | 1-950 | ABC transporter A family member 9 | |||
Sequence: MTLREGLPLFHQQFTALFKKNLLLSWRNKRATCLHLFSSFFFILLIFSIEESSKASDLTSTRHKNVTDPKALVSLPILPCEDKFFVRLPCFDFVWSGNQSRRVTDIVSAIMANNPGRPIPTNKVQSFTKPEEVDAWFMSHPSQVTGALHFVEKNATVISYGIQTNSSSEKKRGRREDPTFKFLVPLQIAAEREIARSLIGDPKFSWDFGFKEFARPAIGGEVIISAFYLMGPVFFLAFSMFGFVLQLGSVVTEKELKLREAMTTMGVYESAYWLSWLIWEGILTFVSSLFLVLFGMMFQFEFFLKNSFVLVFLLFFLFQFNMIGLAFALSSIISKSSSATTVGFLVFLVGFITQIVTTAGFPYSSAYSIGSRVIWSLFPPNTFSAGLQLLLEATSSPGDSGISWSERAICAGGESTCVITTNKIYIWLVGTFFFWFVLALYFDNIIPNASGVRKSIFYFLKPSYWTGKEGNKVEEGSICSCIGSVPPVEHITPEDEDVLEEEILVKQQAMDGRVDPNIAVQIHGLAKTYPGTTKLGCCKCTKTSPFHAVKGLWMNIAKDQLFCLLGPNGAGKTTTISCLTGINPVTGGDAKIYGNSIRSSVGMSNIRKMIGVCPQFDILWDALSSEEHLHLFASIKGLPPSSIKSIAEKLLVDVKLTGSAKIRAGSYSGGMKRRLSVAIALIGDPKLVFLDEPTTGMDPITRRHVWDIIQESKKGRAIILTTHSMEEADILSDRIGIMAKGRLRCIGTSIRLKSRFGTGFVATVSFIENKKDGAPEPLKRFFKERLKVEPTEENKAFMTFVIPHDKEQLLKGFFAELQDRESEFGIADIQLGLATLEEVFLNIARRAELESATVEGTMVTLELESGIAVEIPVGARFVGIPGTENAENPRGLMVEVYWQQDGSGSMCISGHSAEMRIPENVSVIYEPSSQVLGHGQRRVRGIVIDYESNN |
Proteomic databases
PTM databases
Expression
Tissue specificity
Highly expressed in siliques. Detected in seedlings, rosette leaves, stems and flowers.
Developmental stage
Expressed during the middle and late stages of seed development.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 520-765 | ABC transporter | ||||
Sequence: VQIHGLAKTYPGTTKLGCCKCTKTSPFHAVKGLWMNIAKDQLFCLLGPNGAGKTTTISCLTGINPVTGGDAKIYGNSIRSSVGMSNIRKMIGVCPQFDILWDALSSEEHLHLFASIKGLPPSSIKSIAEKLLVDVKLTGSAKIRAGSYSGGMKRRLSVAIALIGDPKLVFLDEPTTGMDPITRRHVWDIIQESKKGRAIILTTHSMEEADILSDRIGIMAKGRLRCIGTSIRLKSRFGTGFVATVS |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length950
- Mass (Da)105,431
- Last updated2001-03-01 v1
- ChecksumBEC9BE912192DB5E
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB010069 EMBL· GenBank· DDBJ | BAB10073.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED97510.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002688 EMBL· GenBank· DDBJ | ANM69292.1 EMBL· GenBank· DDBJ | Genomic DNA |