Q9FLN0 · GLIP1_ARATH

Function

function

Confers resistance to the necrotrophic fungus Alternaria brassicicola. Possesses lipase and antimicrobial activities that directly disrupt fungal spore integrity. Triggers systemic resistance, mostly by the ethylene-dependent pathway.

Features

Showing features for active site.

137450100150200250300350
TypeIDPosition(s)Description
Active site44Nucleophile
Active site338Charge relay system
Active site341Charge relay system

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functionlipase activity
Biological Processdefense response to bacterium
Biological Processdefense response to fungus
Biological Processinduced systemic resistance, ethylene mediated signaling pathway
Biological Processjasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway
Biological Processlipid catabolic process
Biological Processresponse to fungus
Biological Processresponse to salicylic acid
Biological Processsystemic acquired resistance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GDSL esterase/lipase 1
  • EC number
  • Alternative names
    • Extracellular lipase 1

Gene names

    • Name
      GLIP1
    • ORF names
      MEE6.6
    • Ordered locus names
      At5g40990

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9FLN0

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Secreted
Note: Secreted upon salicylic acid treatment.

Keywords

Phenotypes & Variants

Disruption phenotype

In the resistant cv. Columbia (glip1-1 and glip1-2), confers susceptibility to A.brassicicola.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 55 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-25
ChainPRO_000036733426-374GDSL esterase/lipase 1
Glycosylation34N-linked (GlcNAc...) asparagine
Glycosylation184N-linked (GlcNAc...) asparagine
Glycosylation203N-linked (GlcNAc...) asparagine
Glycosylation330N-linked (GlcNAc...) asparagine
Glycosylation360N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Induction

By ethylene.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the 'GDSL' lipolytic enzyme family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    374
  • Mass (Da)
    41,706
  • Last updated
    2001-03-01 v1
  • Checksum
    3CF3297DEB910456
MENSQLVSITFLAYTIIISIGSINCIDNNNLVTNQSALFVFGDSVFDAGNNNYIDTLSSVRSNYWPYGQTTFKSPTGRVSDGRLIPDFIAEYAWLPLIPPNLQPFNGNSQFAYGVNFASGGAGALVGTFSGLVINLRTQLNNFKKVEEMLRSKLGDAEGKRVISRAVYLFHIGLNDYQYPFTTNSSLFQSISNEKYVDYVVGNMTDVFKEVYNLGGRKFGILNTGPYDCAPASLVIDQTKIRSCFQPVTELINMHNEKLLNGLRRLNHELSGFKYALHDYHTSLSERMNDPSKYGFKEGKKACCGSGPLRGINTCGGRMGLSQSYELCENVTDYLFFDPFHLTEKANRQIAELIWSGPTNITGPYNLKALFELN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB010072
EMBL· GenBank· DDBJ
BAB09701.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED94623.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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