Q9FKM5 · XRCC3_ARATH
- ProteinDNA repair protein XRCC3 homolog
- GeneXRCC3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids304 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Plays essential roles in DNA damage repair in both somatic and meiotic cells. It is important for postsynaptic events following pachytene in meiosis. It is also required for DNA cross-links repair and is involved in double strand breaks (DSBs) repair.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 46-53 | ATP (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent DNA damage sensor activity | |
Molecular Function | single-stranded DNA binding | |
Biological Process | double-strand break repair | |
Biological Process | double-strand break repair via synthesis-dependent strand annealing | |
Biological Process | meiotic cell cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameDNA repair protein XRCC3 homolog
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FKM5
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Expression
Tissue specificity
Detected in various tissues. More expressed in reproductive tissues than in vegetative tissues, with the highest level in young flower buds.
Induction
By genotoxic stress and by DNA damage.
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length304
- Mass (Da)33,732
- Last updated2001-03-01 v1
- MD5 ChecksumA781A4BAE55349A7EF8CADD915990761
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB062455 EMBL· GenBank· DDBJ | BAB64342.1 EMBL· GenBank· DDBJ | mRNA | ||
AB073492 EMBL· GenBank· DDBJ | BAB70684.1 EMBL· GenBank· DDBJ | mRNA | ||
AJ438908 EMBL· GenBank· DDBJ | CAD27641.1 EMBL· GenBank· DDBJ | mRNA | ||
AJ438909 EMBL· GenBank· DDBJ | CAD27642.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY032998 EMBL· GenBank· DDBJ | AAK54457.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB011482 EMBL· GenBank· DDBJ | BAB08781.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96903.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96904.1 EMBL· GenBank· DDBJ | Genomic DNA |