Q9FK13 · PDV1_ARATH
- ProteinPlastid division protein PDV1
- GenePDV1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids272 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Component of the plastid division machinery (PubMed:16998069).
Required to mediate the dissociation of ARC5/DRP5B from plastid outer envelope membranes (OEMs) at the midplastid constriction site in the cytoplasm, thus triggering ARC5/DRP5B ring turnover at the chloroplast division site (PubMed:16998069, PubMed:32005784).
Binding to phosphatidylinositol 4-phosphate (PI4P) modulates negatively chloroplast division (PubMed:25736058).
Required to mediate the dissociation of ARC5/DRP5B from plastid outer envelope membranes (OEMs) at the midplastid constriction site in the cytoplasm, thus triggering ARC5/DRP5B ring turnover at the chloroplast division site (PubMed:16998069, PubMed:32005784).
Binding to phosphatidylinositol 4-phosphate (PI4P) modulates negatively chloroplast division (PubMed:25736058).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chloroplast outer membrane | |
Molecular Function | phosphatidylinositol-4-phosphate binding | |
Biological Process | chloroplast fission | |
Biological Process | response to gibberellin |
Names & Taxonomy
Protein names
- Recommended namePlastid division protein PDV1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FK13
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Plastid, chloroplast outer membrane ; Single-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-206 | Cytoplasmic | ||||
Sequence: MGEMEIEEIEAVLEKIWDLHDKLSDEIHLISKSHFLKSVKPSNRSEKRKNPHGNSGEDKRPGYVFIKGFAVDDNDSTIQEAKSLNAIRTALENLEDQLEFFHTIHTQQRTEKDVAIARLEQSRILLAMRLAEHHGKNYGVLEEALAFVGSIKSNSHYVSPDHLYDSSRNPDGANSIPDGIESNFVINAFASTFGFAKRALGFNHVK | ||||||
Transmembrane | 207-225 | Helical | ||||
Sequence: GVLGNAAIFAISVVAMLHL | ||||||
Topological domain | 226-272 | Chloroplast intermembrane | ||||
Sequence: HQVATSEHHLQKKEDRFYRSQQRKTYGRDKSSADRSLDHLDVMMARG |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Reduced number of constricted and large chloroplasts due to a blocked plastid division (PubMed:16998069, PubMed:32005784).
Accumulation of ARC5/DRP5B in the plastid outer envelope membranes (OEMs) at the midplastid constriction site in the cytoplasm (PubMed:32005784).
Accumulation of ARC5/DRP5B in the plastid outer envelope membranes (OEMs) at the midplastid constriction site in the cytoplasm (PubMed:32005784).
Features
Showing features for mutagenesis.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Mutagenesis | 272 | In pdv1-2; reduced number of constricted and large chloroplasts, impaired subchloroplastic localization to the division site in the plastid outermembrane. Impaired interaction with CDP1/PARC6. | ||||
Sequence: G → D |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 27 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000406943 | 1-272 | Plastid division protein PDV1 | |||
Sequence: MGEMEIEEIEAVLEKIWDLHDKLSDEIHLISKSHFLKSVKPSNRSEKRKNPHGNSGEDKRPGYVFIKGFAVDDNDSTIQEAKSLNAIRTALENLEDQLEFFHTIHTQQRTEKDVAIARLEQSRILLAMRLAEHHGKNYGVLEEALAFVGSIKSNSHYVSPDHLYDSSRNPDGANSIPDGIESNFVINAFASTFGFAKRALGFNHVKGVLGNAAIFAISVVAMLHLHQVATSEHHLQKKEDRFYRSQQRKTYGRDKSSADRSLDHLDVMMARG |
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed in young developing leaves, root tips, shoot apices, and flower buds (sepals, petals, stamens, and pistils), but not in developed tissues.
Induction
Induced by gibberellic acid (GA).
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 40-56 | Basic and acidic residues | ||||
Sequence: KPSNRSEKRKNPHGNSG | ||||||
Region | 40-61 | Disordered | ||||
Sequence: KPSNRSEKRKNPHGNSGEDKRP | ||||||
Coiled coil | 78-102 | |||||
Sequence: IQEAKSLNAIRTALENLEDQLEFFH |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length272
- Mass (Da)30,675
- Last updated2001-03-01 v1
- ChecksumD6EA6676B3DB9CFE
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 40-56 | Basic and acidic residues | ||||
Sequence: KPSNRSEKRKNPHGNSG | ||||||
Sequence conflict | 154 | in Ref. 4; AAM64850 | ||||
Sequence: N → T | ||||||
Sequence conflict | 176-181 | in Ref. 4; AAM64850 | ||||
Sequence: IPDGIE → TPYGIK | ||||||
Sequence conflict | 188 | in Ref. 4; AAM64850 | ||||
Sequence: A → S | ||||||
Sequence conflict | 216 | in Ref. 4; AAM64850 | ||||
Sequence: A → T | ||||||
Sequence conflict | 258 | in Ref. 4; AAM64850 | ||||
Sequence: A → G |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB252216 EMBL· GenBank· DDBJ | BAF36494.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB252218 EMBL· GenBank· DDBJ | BAF36496.1 EMBL· GenBank· DDBJ | mRNA | ||
AB013388 EMBL· GenBank· DDBJ | BAB09790.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96332.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY087298 EMBL· GenBank· DDBJ | AAM64850.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AK221634 EMBL· GenBank· DDBJ | BAD95268.1 EMBL· GenBank· DDBJ | mRNA | ||
BT024498 EMBL· GenBank· DDBJ | ABD19679.1 EMBL· GenBank· DDBJ | mRNA |