Q9FJ55 · CIPKJ_ARATH
- ProteinCBL-interacting serine/threonine-protein kinase 19
- GeneCIPK19
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids483 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 34-42 | ATP (UniProtKB | ChEBI) | |||
Binding site | 57 | ATP (UniProtKB | ChEBI) | |||
Active site | 150 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | histone H2AS1 kinase activity | |
Molecular Function | protein serine kinase activity | |
Biological Process | protein phosphorylation | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCBL-interacting serine/threonine-protein kinase 19
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FJ55
Proteomes
Organism-specific databases
Genome annotation databases
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000337220 | 1-483 | CBL-interacting serine/threonine-protein kinase 19 | ||
Modified residue | 172 | Phosphoserine | |||
Modified residue | 186 | Phosphothreonine | |||
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | IntAct | |
---|---|---|---|---|---|
BINARY | Q9FJ55 | DSPTP1 Q9ZR37 | 3 | EBI-16967606, EBI-25512239 | |
BINARY | Q9FJ55 | PP2AA1 Q38845 | 3 | EBI-16967606, EBI-1645478 | |
BINARY | Q9FJ55 | TCP23 Q9LQF0 | 3 | EBI-16967606, EBI-15192297 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 28-282 | Protein kinase | |||
Region | 168-197 | Activation loop | |||
Region | 313-338 | Disordered | |||
Domain | 340-364 | NAF | |||
Region | 367-396 | PPI | |||
Region | 459-483 | Disordered | |||
Domain
The activation loop within the kinase domain is the target of phosphorylation/activation by upstream protein kinases. The PPI motif mediates the interaction with the ABI (abscisic acid-insensitive) phosphatases (By similarity).
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length483
- Mass (Da)54,616
- Last updated2001-03-01 v1
- Checksum2CF0E948F2A07BF9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY030303 EMBL· GenBank· DDBJ | AAK50347.1 EMBL· GenBank· DDBJ | mRNA | ||
AB016870 EMBL· GenBank· DDBJ | BAB09309.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED95302.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ447041 EMBL· GenBank· DDBJ | ABE66223.1 EMBL· GenBank· DDBJ | mRNA |