Q9FHH2 · SMAX1_ARATH
- ProteinProtein SUPPRESSOR OF MAX2 1
- GeneSMAX1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids990 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Probable component of a transcriptional corepressor complex that acts downstream of MAX2 to negatively regulate karrikins/strigolactone responses (PubMed:23893171, PubMed:26546447).
Probable target of MAX2 during germination and seedling photomorphogenesis (PubMed:26546447).
Acts probably specifically in the karrikin pathway (PubMed:26754282).
Probable target of MAX2 during germination and seedling photomorphogenesis (PubMed:26546447).
Acts probably specifically in the karrikin pathway (PubMed:26754282).
GO annotations
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Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Biological Process | response to karrikin | |
Biological Process | response to strigolactone | |
Biological Process | seed germination | |
Biological Process | seedling development |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProtein SUPPRESSOR OF MAX2 1
- Short namesAtSMXL1
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FHH2
Proteomes
Organism-specific databases
Genome annotation databases
Phenotypes & Variants
Disruption phenotype
Low seed dormancy and short hypocotyls (PubMed:23893171).
Suppresses max2 phenotypes associated with karrikin-KAI2-regulated growth (PubMed:26546447).
Smax1 and smxl2 double mutants have substantial reduction in hypocotyl elongation (PubMed:26754282).
Suppresses max2 phenotypes associated with karrikin-KAI2-regulated growth (PubMed:26546447).
Smax1 and smxl2 double mutants have substantial reduction in hypocotyl elongation (PubMed:26754282).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 81 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000435710 | 1-990 | Protein SUPPRESSOR OF MAX2 1 | |||
Sequence: MRAGLSTIQQTLTPEAATVLNQSIAEAARRNHGQTTPLHVAATLLASPAGFLRRACIRSHPNSSHPLQCRALELCFSVALERLPTATTTPGNDPPISNALMAALKRAQAHQRRGCPEQQQQPLLAVKVELEQLIISILDDPSVSRVMREASFSSPAVKATIEQSLNNSVTPTPIPSVSSVGLNFRPGGGGPMTRNSYLNPRLQQNASSVQSGVSKNDDVERVMDILGRAKKKNPVLVGDSEPGRVIREILKKIEVGEVGNLAVKNSKVVSLEEISSDKALRIKELDGLLQTRLKNSDPIGGGGVILDLGDLKWLVEQPSSTQPPATVAVEIGRTAVVELRRLLEKFEGRLWFIGTATCETYLRCQVYHPSVETDWDLQAVSVAAKAPASGVFPRLANNLESFTPLKSFVPANRTLKCCPQCLQSYERELAEIDSVSSPEVKSEVAQPKQLPQWLLKAKPVDRLPQAKIEEVQKKWNDACVRLHPSFHNKNERIVPIPVPITLTTSPYSPNMLLRQPLQPKLQPNRELRERVHLKPMSPLVAEQAKKKSPPGSPVQTDLVLGRAEDSEKAGDVQVRDFLGCISSESVQNNNNISVLQKENLGNSLDIDLFKKLLKGMTEKVWWQNDAAAAVAATVSQCKLGNGKRRGVLSKGDVWLLFSGPDRVGKRKMVSALSSLVYGTNPIMIQLGSRQDAGDGNSSFRGKTALDKIAETVKRSPFSVILLEDIDEADMLVRGSIKQAMDRGRIRDSHGREISLGNVIFVMTASWHFAGTKTSFLDNEAKLRDLASESWRLRLCMREKFGKRRASWLCSDEERLTKPKKEHGSGLSFDLNQAADTDDGSHNTSDLTTDNDQDEQGFSGKLSLQCVPFAFHDMVSRVDDAVAFRAVDFAAVRRRITETLSERFETIIGESLSVEVEEEALQRILSGVWLGQTELEEWIEKAIVPVLSQLKARVSSSGTYGDCTVARLELDEDSGERNAGDLLPTTITLAV |
Proteomic databases
PTM databases
Expression
Tissue specificity
Highly expressed in dry seeds. Expressed in seedlings, rosette leaves and senescing leaves. Detected in roots and axillary shoots (PubMed:23893171).
Expressed in the primary rosette buds and expanding leaves of adult rosettes, the vasculature of the hypocotyls, cotyledons, and mature roots, in the midvein and petioles of young leaves, the young leaf periphery, stomata, and the root caps (PubMed:26546447).
Expressed in the primary rosette buds and expanding leaves of adult rosettes, the vasculature of the hypocotyls, cotyledons, and mature roots, in the midvein and petioles of young leaves, the young leaf periphery, stomata, and the root caps (PubMed:26546447).
Induction
Up-regulated by karrikins treatments (PubMed:20351290).
Under MAX2-dependent negative feedback regulation (PubMed:23893171).
Under MAX2-dependent negative feedback regulation (PubMed:23893171).
Developmental stage
Peak of expression in seeds during maturation.
Gene expression databases
Interaction
Subunit
Interacts probably with TPL/TPR in an EAR-motif dependent manner. Interacts with TPL, TPR1, TPR2 and TPR4.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-167 | Clp R | ||||
Sequence: IQQTLTPEAATVLNQSIAEAARRNHGQTTPLHVAATLLASPAGFLRRACIRSHPNSSHPLQCRALELCFSVALERLPTATTTPGNDPPISNALMAALKRAQAHQRRGCPEQQQQPLLAVKVELEQLIISILDDPSVSRVMREASFSSPAVKATIEQSLNN | ||||||
Region | 12-83 | Repeat 1 | ||||
Sequence: LTPEAATVLNQSIAEAARRNHGQTTPLHVAATLLASPAGFLRRACIRSHPNSSHPLQCRALELCFSVALERL | ||||||
Region | 96-167 | Repeat 2 | ||||
Sequence: ISNALMAALKRAQAHQRRGCPEQQQQPLLAVKVELEQLIISILDDPSVSRVMREASFSSPAVKATIEQSLNN | ||||||
Region | 818-855 | Disordered | ||||
Sequence: PKKEHGSGLSFDLNQAADTDDGSHNTSDLTTDNDQDEQ | ||||||
Motif | 828-832 | EAR | ||||
Sequence: FDLNQ |
Domain
Contains 1 EAR motif required for the interaction with TPR2.
Sequence similarities
Belongs to the ClpA/ClpB family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length990
- Mass (Da)108,710
- Last updated2001-03-01 v1
- ChecksumA0BA396F566466CB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB018118 EMBL· GenBank· DDBJ | BAB09589.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96941.1 EMBL· GenBank· DDBJ | Genomic DNA |