Q9FGN0 · COG7_ARATH
- ProteinConserved oligomeric Golgi complex subunit 7
- GeneCOG7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids836 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Required for normal Golgi function (PubMed:18422605).
Necessary for embryo development and pigmentation, especially for the expansion of cells and organs, and for the formation of the organized shoot apical meristem (SAM) (PubMed:18422605).
Probably involved in the generation of the extra-cellular matrix (PubMed:18422605).
Necessary for embryo development and pigmentation, especially for the expansion of cells and organs, and for the formation of the organized shoot apical meristem (SAM) (PubMed:18422605).
Probably involved in the generation of the extra-cellular matrix (PubMed:18422605).
GO annotations
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Aspect | Term | |
---|---|---|
Cellular Component | Golgi membrane | |
Cellular Component | Golgi transport complex | |
Biological Process | embryo development ending in seed dormancy | |
Biological Process | Golgi organization | |
Biological Process | intracellular protein transport | |
Biological Process | meristem development | |
Biological Process | meristem structural organization | |
Biological Process | protein retention in Golgi apparatus | |
Biological Process | shoot system morphogenesis | |
Biological Process | unidimensional cell growth |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameConserved oligomeric Golgi complex subunit 7
- Short namesCOG complex subunit 7
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9FGN0
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Peripheral membrane protein
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Abnormal coloration and morphology of embryos leading to bushy plants, with aberrant organization of the shoot apical meristem (SAM) and unexpanded leaves with irregular phyllotaxy, as well as small and round epidermal cells (PubMed:18422605).
Disrupted hydrophobic layers of epidermal cells (PubMed:18422605).
Mislocalization of Golgi proteins (e.g. ERD2) and altered size of the Golgi apparatus (PubMed:18422605).
Disrupted hydrophobic layers of epidermal cells (PubMed:18422605).
Mislocalization of Golgi proteins (e.g. ERD2) and altered size of the Golgi apparatus (PubMed:18422605).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 57 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000448529 | 1-836 | Conserved oligomeric Golgi complex subunit 7 | |||
Sequence: MMLDLGPFSDEKFDAKRWVNSSCQARHPQDSLEKHLVDLEMKLQIASEEIGASLEEQSGGALLRVPRATRDVLRLRDDAVSLRGSVAGILQKLKKAEGSSADCIAALARVDNVKQRMEAAYKTLQDAAGLTQLSSTVEDVFASGDLPRAAETLASMRNCLSAVGEVAEFANVRKQLEVLEDRLEAMVQPRLTDALTYHKVDVAQDLRVILIRIGRFKSLELQYSKVRLKPIKQLWEDFDTKQRANKLANERSESQRLSSGDEFQSTSSQTSFASWLTSFYDELLLYLEQEWKWCMVAFPDDYMTLVPKLLVETMGVLGASFVSRLNLATGDAVPETKALAKGVMDLLSGDLPKGINIQTKHLEALIELHNVTGSFARNIQHLFAESELRILIDTLKAVYSPFESFKQKYGKMERAILSSEIAVVDLRGAVTRGVGAQGIELSETVRRMEESIPQVVVLLEAAVERCIGFTGGSEADELILALDDIMLQYISMLQETLKSLRVVCGVDGTGDGVGSKKDASAEKRESSRKMDLTSNEEWSIVQGALQILTVADCLTSRSSVFEASLRATLARLNSSLSISLFGTNLDHNLSHLKSEQTAGDLSMAGRASMDVAAIRLVDVPEKAHKLLNLLEQSKDPRFHALPLASQRVAAFADTVNELVYDVLISKVRQRLGEVSRLPIWSSVEEQTAFPLPNFSSYPQSYVTSVGEYLLTLPQQLEPLAEGISTNGDSNNEDAQFFATEWMFKVAEGATALYMDQLRGIQYISDRGAQQLSVDIEYLSNVLSALSMPIPPVLATFQTCLATPRGELKDVMKSEAGNELDCPTANLVCKMRRISFD |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 29-49 | |||||
Sequence: QDSLEKHLVDLEMKLQIASEE | ||||||
Coiled coil | 107-127 | |||||
Sequence: LARVDNVKQRMEAAYKTLQDA | ||||||
Region | 246-265 | Disordered | ||||
Sequence: KLANERSESQRLSSGDEFQS | ||||||
Compositional bias | 251-265 | Polar residues | ||||
Sequence: RSESQRLSSGDEFQS |
Sequence similarities
Belongs to the COG7 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length836
- Mass (Da)92,259
- Last updated2001-03-01 v1
- ChecksumA875BAE2F18F61BD
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 251-265 | Polar residues | ||||
Sequence: RSESQRLSSGDEFQS | ||||||
Sequence conflict | 284 | in Ref. 1; BAG15881 | ||||
Sequence: L → R | ||||||
Sequence conflict | 612 | in Ref. 5; BAF00649 | ||||
Sequence: A → P | ||||||
Sequence conflict | 724 | in Ref. 2; AIU51104 | ||||
Sequence: Missing | ||||||
Sequence conflict | 825 | in Ref. 1; BAG15881 | ||||
Sequence: N → S |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB429304 EMBL· GenBank· DDBJ | BAG15881.1 EMBL· GenBank· DDBJ | mRNA | ||
KM400475 EMBL· GenBank· DDBJ | AIU51104.1 EMBL· GenBank· DDBJ | mRNA | ||
AB025621 EMBL· GenBank· DDBJ | BAB09754.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED96080.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK228749 EMBL· GenBank· DDBJ | BAF00649.1 EMBL· GenBank· DDBJ | mRNA |