Q9FFA7 · RUP2_ARATH

Function

function

Functions in association with RUP1 as repressor of UV-B-induced photomorphogenesis mediated by UVR8 and HY5. Plays a crucial negative feedback regulatory role downstream of UVR8-COP1 to inhibit UVR8 function, balance UV-B-specific responses and ensure normal plant growth. Is involved in the regulation of photoperiodic flowering and vegetative development. May act as negative regulator of photoperiodic flowering by suppressing flowering through the action of CONSTANS (CO) and FLOWERING LOCUS T (FT).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentCul4-RING E3 ubiquitin ligase complex
Cellular Componentcytosol
Cellular Componentnucleus
Biological Processchloroplast organization
Biological Processflower development
Biological Processregulation of protein-containing complex assembly
Biological Processresponse to UV-B

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    WD repeat-containing protein RUP2
  • Alternative names
    • Protein EARLY FLOWERING BY OVEREXPRESSION 2
    • Protein REPRESSOR OF UV-B PHOTOMORPHOGENESIS 2

Gene names

    • Name
      RUP2
    • Synonyms
      EFO2
    • ORF names
      MRO11.23
    • Ordered locus names
      At5g23730

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9FFA7
  • Secondary accessions
    • Q94BR3

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Small stunted leaves and early flowering under short days conditions.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 42 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004217211-368WD repeat-containing protein RUP2

Proteomic databases

PTM databases

Expression

Induction

Circadian-regulation. Expression increases during the dark phase with a peak at the beginning of the light phase and then decreases to reach the lowest expression at the end of the light phase. Induced by UV-B.

Gene expression databases

Interaction

Subunit

Interacts with UVR8.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY Q9FFA7UVR8 Q9FN033EBI-15889073, EBI-2407499

Protein-protein interaction databases

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat38-77WD 1
Repeat97-138WD 2
Repeat141-184WD 3
Repeat192-232WD 4
Repeat236-276WD 5
Repeat279-318WD 6
Repeat330-368WD 7

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    368
  • Mass (Da)
    40,002
  • Last updated
    2001-03-01 v1
  • Checksum
    3860809FFF0C358C
MNTLHPHKQQQEQAQQQEEARYEWDLSLSTVVSSSSSSASDVIGAIEFDPTDNIVATAGISRKIRFYGLPSLLRNNAVSGTGVSFVDQATACEYYICTPAKLSSLRWRPGSGGRVIGSGDYDGVVMEYDLEKRTPVFERDEHGGRRVWSVDYTRHGGASTVGASGSDDGTMQVWDPRCPPEESVGVVRPAGICRSAVCCVEFDPSGGPAVAVGCADRKGYVYDIRKLVDPALTLQGHTKTVSYVRFLDGGTVVTAGTDGCLKLWSVEDGRVIRTYEGHVNNRNFVGLSVWRNGALFGCGSENNRVFVYDRRWGKPVWVDGFEPVGMNSGSDKRFVSSVCWRQSGVDQCTLVAGGSDGVLQVYVGKRKP

Sequence caution

The sequence AAK64045.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB005244
EMBL· GenBank· DDBJ
BAB10046.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED93205.1
EMBL· GenBank· DDBJ
Genomic DNA
AY039941
EMBL· GenBank· DDBJ
AAK64045.1
EMBL· GenBank· DDBJ
mRNA Different initiation
BT015119
EMBL· GenBank· DDBJ
AAT71991.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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