Q9ERE2 · KRT81_MOUSE

  • Protein
    Keratin, type II cuticular Hb1
  • Gene
    Krt81
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Miscellaneous

There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentkeratin filament
Molecular Functionstructural constituent of skin epidermis
Biological Processintermediate filament organization
Biological Processkeratinization

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Keratin, type II cuticular Hb1
  • Alternative names
    • Keratin-81
      (K81)
    • Type II hair keratin Hb1

Gene names

    • Name
      Krt81
    • Synonyms
      Krt2-19

Organism names

  • Taxonomic identifier
  • Strains
    • C57BL/6J
    • C3H/HeN
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9ERE2
  • Secondary accessions
    • E9QLY5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, cross-link.

TypeIDPosition(s)Description
ChainPRO_00003616901-481Keratin, type II cuticular Hb1
Cross-link212Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in dorsal skin.

Gene expression databases

Interaction

Subunit

Heterotetramer of two type I and two type II keratins.

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-106Head
Domain106-417IF rod
Region107-141Coil 1A
Region142-151Linker 1
Region152-252Coil 1B
Region253-269Linker 12
Region270-413Coil 2
Region414-481Tail

Sequence similarities

Belongs to the intermediate filament family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    481
  • Mass (Da)
    52,863
  • Last updated
    2013-10-16 v2
  • Checksum
    DEF13B624C76C80A
MTCGSGFCGRAFSCASACGPRPGRCCISAAPYRGISCYRGLSGGFGSQSVCGAFRSGSCGRSFGYRSGGICGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKHEEKEQIKCLNSKFAAFIDKVRFLEQQNKLLETKWQFYQNRKCCESNMEPLFEGYIEALRREAECVEADSGRLAAELNHAQESMEGYKKRYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANAEALTQETDFLRRMYDEETRILHSHISDTSIVVKMDNSRDLNMDCVVAEIKAQYDDIASRSRAEAESWYRTKCEEIKATVIRHGETLRRTREEINELNRMIQRLTAEIENAKCQNTKLEAAVTQSEQQGEAALADARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDVEITTYRRLLEGEEQRLCEGVGAVNVCVSSSRGGVVCGDLCVSGSRPVIGSACSAPCSGNLAVNTGLCAPCGSAVSCGRKC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC103674
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC157583
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AF312018
EMBL· GenBank· DDBJ
AAG34120.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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