Q9EQ44 · V1R41_MOUSE

  • Protein
    Vomeronasal type-1 receptor 41
  • Gene
    Vmn1r41
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Putative pheromone receptor implicated in the regulation of social and reproductive behavior.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionpheromone receptor activity
Biological Processresponse to pheromone
Biological Processsensory perception of chemical stimulus

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Vomeronasal type-1 receptor 41
  • Alternative names
    • Vomeronasal type-1 receptor A12
    • Vomeronasal type-1 receptor B9

Gene names

    • Name
      Vmn1r41
    • Synonyms
      V1ra12
      , V1rb9

Organism names

  • Taxonomic identifier
  • Strain
    • 129/SvJ
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9EQ44
  • Secondary accessions
    • Q8VIC4

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-20Extracellular
Transmembrane21-41Helical; Name=1
Topological domain42-49Cytoplasmic
Transmembrane50-70Helical; Name=2
Topological domain71-93Extracellular
Transmembrane94-114Helical; Name=3
Topological domain115-134Cytoplasmic
Transmembrane135-155Helical; Name=4
Topological domain156-190Extracellular
Transmembrane191-211Helical; Name=5
Topological domain212-238Cytoplasmic
Transmembrane239-259Helical; Name=6
Topological domain260-269Extracellular
Transmembrane270-290Helical; Name=7
Topological domain291-310Cytoplasmic

Keywords

Phenotypes & Variants

Disruption phenotype

Mice lacking all but one V1ra and V1rb gene (12% of the V1r repertoire) show a lack of chemosensory response to a subset of known pheromonal ligands and changes in maternal aggression as well as male reproductive behavior.

PTM/Processing

Features

Showing features for chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00002399811-310Vomeronasal type-1 receptor 41
Disulfide bond85↔172
Glycosylation159N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    310
  • Mass (Da)
    35,228
  • Last updated
    2001-03-01 v1
  • Checksum
    19D8ED1740455DAE
MNKANLLYTDTNMKTFLFSEVSVGISANSMLFIVHICILLGENRPKPINLYIAFLSLTQLMLLITMGLIVADMFMSQGIWDSITCQSLIYLHRLLRGLTLCATCLLNVLWTITLSPRSSCLTKFKHKSPHHISGAFLFFCALYMSFSSHLFLSIIATPNLTSEDFMYVTQSCSLLSMSYSRTSMFSTAIAIREAFLISLFALCSGYMVALLWRHKKQAWDLHSTNVSSKSSPEQRATRTIMLLMSFFVVLYVLENAVFHSRMKFKDGSMLYCVQIIVSHSYATVSPFVLICTEKRMIKFWGSMFGRIVNI

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2I3BPT8A0A2I3BPT8_MOUSEVmn1r4196
A0A2I3BQ84A0A2I3BQ84_MOUSEVmn1r4181
A0A0N4SVQ3A0A0N4SVQ3_MOUSEVmn1r41311

Sequence caution

The sequence BAB79218.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF291495
EMBL· GenBank· DDBJ
AAG42089.1
EMBL· GenBank· DDBJ
Genomic DNA
AB062901
EMBL· GenBank· DDBJ
BAB79218.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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