Q9DTD8 · Q9DTD8_9HEPC
- ProteinGenome polyprotein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids3011 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
Catalytic activity
- ATP + H2O = ADP + H+ + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameGenome polyprotein
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Kitrinoviricota > Flasuviricetes > Amarillovirales > Flaviviridae > Hepacivirus
Accessions
- Primary accessionQ9DTD8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Endoplasmic reticulum membrane ; Peripheral membrane protein
Endoplasmic reticulum membrane ; Single-pass type I membrane protein
Host endoplasmic reticulum membrane ; Multi-pass membrane protein
Host endoplasmic reticulum membrane ; Peripheral membrane protein
Host endoplasmic reticulum membrane ; Single-pass type I membrane protein
Membrane ; Multi-pass membrane protein
Membrane ; Peripheral membrane protein
Membrane ; Single-pass type I membrane protein
Virion membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 719-741 | Helical | ||||
Sequence: YVLLLFLLLADARVCACLWMMLL | ||||||
Transmembrane | 753-779 | Helical | ||||
Sequence: VVLNAASVAGAHGILSFLVFFCAAWYI | ||||||
Transmembrane | 785-804 | Helical | ||||
Sequence: PGAAYALYGVWPLLLLLLAL | ||||||
Transmembrane | 816-836 | Helical | ||||
Sequence: AASCGGAVFIGLAFLTLSPYY | ||||||
Transmembrane | 892-914 | Helical | ||||
Sequence: LLLAILGPLMVLQAGITAVPYFV | ||||||
Transmembrane | 1661-1689 | Helical | ||||
Sequence: WVLVGGVLAALAAYCLTTGSVVIVGRIIL | ||||||
Transmembrane | 1852-1871 | Helical | ||||
Sequence: ILAGYGAGVAGALVAFKVMS | ||||||
Transmembrane | 1883-1903 | Helical | ||||
Sequence: LLPAILSPGALVVGVVCAAIL | ||||||
Transmembrane | 2991-3008 | Helical | ||||
Sequence: WFMLCLLLLSVGVGVYLL |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-75 | Disordered | ||||
Sequence: MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRPEGRA | ||||||
Compositional bias | 47-69 | Basic and acidic residues | ||||
Sequence: RATRKTSERSQPRGRRQPIPKAR | ||||||
Domain | 904-1027 | Peptidase C18 | ||||
Sequence: QAGITAVPYFVRAQGLIRACMLVRKVAGGHYVQMALVKLAALTGTYVYDHLTPLQDWAHVALRDLAVAVEPVVFSDMETKIITWGADTAACGDIILGLPVSARRGKEILLGPADSLEGQGWRLL | ||||||
Domain | 1028-1209 | Peptidase S29 | ||||
Sequence: APITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCINGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWLAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDGRGSLLSPRPVSYLKGSSGGPLLCPSGHVVGIFRAAVCTRGVAKAVDFVPVESMETTMRSP | ||||||
Domain | 1218-1370 | Helicase ATP-binding | ||||
Sequence: PAVPQTFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLSFGAYMSKAHGTDPNIRTGVRTITTGAPITYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSN | ||||||
Domain | 1362-1539 | Helicase C-terminal | ||||
Sequence: NIEEVALSNTGEVPFYGKAIPIEAIKGGRHLIFCHSKKKCDELAAKLSALGLNAVAYYRGLDVSVIPTNGDVVVVATDALMTGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSIR | ||||||
Region | 2188-2221 | Disordered | ||||
Sequence: RRRLARGSPPSLASSSASQLSAPSLKATCTTHHD | ||||||
Compositional bias | 2196-2218 | Polar residues | ||||
Sequence: PPSLASSSASQLSAPSLKATCTT | ||||||
Compositional bias | 2352-2370 | Polar residues | ||||
Sequence: TFSSSGSSAVDSGTATAPP | ||||||
Region | 2352-2408 | Disordered | ||||
Sequence: TFSSSGSSAVDSGTATAPPDQASDDGDKESDVESYSSMPPLEGEPGDPDLSDGSWST | ||||||
Domain | 2634-2752 | RdRp catalytic | ||||
Sequence: PMGFSYDTRCFDSTVTENDIRVEESIYQCCDLSPEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRAAKLQDCTMLVNGDDLVVICDSAGVQED |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,011
- Mass (Da)326,853
- Last updated2001-03-01 v1
- Checksum068D3BDF753F184D
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 47-69 | Basic and acidic residues | ||||
Sequence: RATRKTSERSQPRGRRQPIPKAR | ||||||
Compositional bias | 2196-2218 | Polar residues | ||||
Sequence: PPSLASSSASQLSAPSLKATCTT | ||||||
Compositional bias | 2352-2370 | Polar residues | ||||
Sequence: TFSSSGSSAVDSGTATAPP |