Q9DRA1 · RDRP_BOTVF
- ProteinRNA replication protein
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1896 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
RNA replication protein replicates the viral genomic RNA. The central part of this protein possibly functions as an ATP-binding helicase and/or methyltransferase (Probable).
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | mRNA methyltransferase activity | |
Molecular Function | RNA binding | |
Molecular Function | RNA helicase activity | |
Molecular Function | RNA-dependent RNA polymerase activity | |
Biological Process | DNA-templated transcription | |
Biological Process | methylation | |
Biological Process | mRNA modification | |
Biological Process | RNA processing | |
Biological Process | viral RNA genome replication |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameRNA replication protein
Including 3 domains:
- Recommended nameRNA-directed RNA polymerase
- EC number
- Recommended nameHelicase
- EC number
- Recommended nameMethyltransferase
- EC number
Gene names
Organism names
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Kitrinoviricota > Alsuviricetes > Tymovirales > Gammaflexiviridae > Mycoflexivirus > Botrytis virus F
- Virus hosts
Accessions
- Primary accessionQ9DRA1
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000402499 | 1-1896 | RNA replication protein | |||
Sequence: MAVPLERAFASVTQSFHKDATQGPTTNEYLVARAETQRYAPYAVRKGPAALLAQVGINTIHDSPLSHSHPACYALNAFHFLKVIPRYLHGKAEVWGTKDNWFRKLQAQIDSQTTTLTHRNYAITARDHVRYPGTVVDHPGSCTAGTLFMHDALQYMTPLDVYTLFATSPEMHSLVATAVIPPESVDRLPAFWPELYQLAYYEDHLCYAPDGNFADAYNQPLAAHQWMTMKSLHGPDFTLSVDVPASRYSHHIFVISKRPGLPDTHRDFMCPDLVELPKDFFPGANKADKLLPRTLVNQMVEYAASVKRATIKDATSRTRAYVKDQKYAAVTPVQQMYLSWFGSGLSQMQFPDRPVTPLDNFATALWYRLLPSRLYRLPATIRNFQLKAFVDQLRTPQYLLHFKLDEYHLSSNDKYSDFYRNESRQASSKDMLSAFEAICFGGAPELEKKILGNNNPAPFATVPNPPSQTALGLATITAAIAFILPNRAARLTRLVARYAIRAVKEIVNPSFLTIPRFGLLSHSIASWLQTDGAVITYGLAPKIASWSAPIWYNAALLAPTDMRSCQVLVDIANDLRFDYRYGTMRLAVTLGLTLLNPFLRRLVLLPFKVLWHSYLPSIKNKLDSMVLMSISTLPDNISVPLLTLRGNLNRQRCPDNKDPTPIHESDDNSTADDKCLHCPIHCLKSKLSEPAASPDTVPEDNPLQEGDLTEEVYAAALAKKDTPPPYPTRNDCLLVALADGLLTKRILWFSCIKMFGNTACWVIHDTGKAFDWMHLKMLAEQLKLNVSIEVAAEHDHHWTGLAKRVGPIDGRKIALRWYPYHWELSDRGREDYGPPPPPPPPSTTEPPPPPNPPAASPYHSPTVEDEPLEEIPLANSNGEFSTFAFDDMAADDLNPAQPLSSLDLDEEPSAKQEPLEPAAIKTSEPEPLVPESEEVFFRPSPTPTPSDATPTPAARAPSSVSNENAQRPRHPLPPVPTGGASAPSNDKLNSAAKQYARLVAGKTRQMTVAQPRSKAYLRDLKRGNIGTIPTAEAEQLDAYIDSWAVNGFNRSVHVIYFCGLPGTGKSRRCMKMTERLLKENKYLAQTVRIVTPTDNLRNSVARQLKPPTESSYSVQTYETPIRQPSLGPVLIVDEYGKMPAGWLETVLFLNPRVQMVIFTADPTQGIFRTRIPDAYCCRIPSSTEAIASYAHEYRRVSDRPAPGVARALGLPTTSRRPGQIETSTELNVDWITVRPEGERAAWHNTWGGKVYTYATCQGETFHRAYQMVINGNTRFWDDRDLFAALTRGSGTLRLIYETQSSKPLPRSTSKLYNALLDFRTDPHKLPLAIEEHVNRYIPSHLRNVNQAVPRRNAASNPDALPSQRILPGGQSTTAEPXQSQASALPTGGEAIDVPALDRQDPQRFPQLKVLPHLCGYIGDYSEASYPEPEHPKTQMLDATFPTYLARNRGWNDPALTDAVTANYKAPEHRDIWVEAVGETTRQVHGSGDDRDVFLEHRGDDKATANITYAKRLRFSQRAANERSIAATKVAGSELFEAFTRAIPLPQETFNDSLLEECRTENDTVHLTSKPLATLINNAERSDPSWSLNMIKLFIKGQTVKKLEKMGSDATAGQSIASFRAEVLLAWGPYARYIDRRIRALLPPHVYIHSRRTNEDFEKFVAAHWDHTRESTDGDYTAYDASQDATFVNFETLLMRRLDFPLDIIEAYVEMKASITSHFGPLAIMRFSGEVWTYLFNTLGNIAFTYAKYEVPSVAQVYGGDDKSINSPITVRTGWSQLVGKFNLVEKPVVGYEPTFCGWRIVPGGIVKDPQLLFWRTRYARIRYDAALWAPGYYDELVLSLKTSDRLMDHMSPNDLAYLQALVRFYTKLSRRLPSLADRRRCNPLPADSPSVVLSRD |
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 60-227 | Alphavirus-like MT | ||||
Sequence: IHDSPLSHSHPACYALNAFHFLKVIPRYLHGKAEVWGTKDNWFRKLQAQIDSQTTTLTHRNYAITARDHVRYPGTVVDHPGSCTAGTLFMHDALQYMTPLDVYTLFATSPEMHSLVATAVIPPESVDRLPAFWPELYQLAYYEDHLCYAPDGNFADAYNQPLAAHQWM | ||||||
Region | 828-991 | Disordered | ||||
Sequence: GREDYGPPPPPPPPSTTEPPPPPNPPAASPYHSPTVEDEPLEEIPLANSNGEFSTFAFDDMAADDLNPAQPLSSLDLDEEPSAKQEPLEPAAIKTSEPEPLVPESEEVFFRPSPTPTPSDATPTPAARAPSSVSNENAQRPRHPLPPVPTGGASAPSNDKLNSA | ||||||
Compositional bias | 831-857 | Pro residues | ||||
Sequence: DYGPPPPPPPPSTTEPPPPPNPPAASP | ||||||
Compositional bias | 951-966 | Polar residues | ||||
Sequence: TPAARAPSSVSNENAQ | ||||||
Domain | 1025-1194 | +RNA virus helicase ATP-binding | ||||
Sequence: IGTIPTAEAEQLDAYIDSWAVNGFNRSVHVIYFCGLPGTGKSRRCMKMTERLLKENKYLAQTVRIVTPTDNLRNSVARQLKPPTESSYSVQTYETPIRQPSLGPVLIVDEYGKMPAGWLETVLFLNPRVQMVIFTADPTQGIFRTRIPDAYCCRIPSSTEAIASYAHEYR | ||||||
Domain | 1195-1327 | +RNA virus helicase C-terminal | ||||
Sequence: RVSDRPAPGVARALGLPTTSRRPGQIETSTELNVDWITVRPEGERAAWHNTWGGKVYTYATCQGETFHRAYQMVINGNTRFWDDRDLFAALTRGSGTLRLIYETQSSKPLPRSTSKLYNALLDFRTDPHKLPL | ||||||
Compositional bias | 1347-1385 | Polar residues | ||||
Sequence: AVPRRNAASNPDALPSQRILPGGQSTTAEPXQSQASALP | ||||||
Region | 1347-1388 | Disordered | ||||
Sequence: AVPRRNAASNPDALPSQRILPGGQSTTAEPXQSQASALPTGG | ||||||
Domain | 1668-1774 | RdRp catalytic | ||||
Sequence: RESTDGDYTAYDASQDATFVNFETLLMRRLDFPLDIIEAYVEMKASITSHFGPLAIMRFSGEVWTYLFNTLGNIAFTYAKYEVPSVAQVYGGDDKSINSPITVRTGW |
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,896
- Mass (Da)212,378
- Last updated2001-03-01 v1
- ChecksumEE15A3ED1387B271
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 831-857 | Pro residues | ||||
Sequence: DYGPPPPPPPPSTTEPPPPPNPPAASP | ||||||
Compositional bias | 951-966 | Polar residues | ||||
Sequence: TPAARAPSSVSNENAQ | ||||||
Compositional bias | 1347-1385 | Polar residues | ||||
Sequence: AVPRRNAASNPDALPSQRILPGGQSTTAEPXQSQASALP |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF238884 EMBL· GenBank· DDBJ | AAG23416.1 EMBL· GenBank· DDBJ | Genomic RNA |