Q9DGC9 · GON2_ORYLA

Function

function

Stimulates the secretion of gonadotropins.

Miscellaneous

Teleost species possess three paralogous GnRHs: mdGnRH and cGnRH-II have been identified in tetrapods; sGnRH has no tetrapod ortholog and is thought to be a duplication of cGnRH-II.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functiongonadotropin hormone-releasing hormone activity
Molecular Functiongonadotropin-releasing hormone receptor binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Progonadoliberin-2
  • Alternative names
    • Chicken-type II gonadotropin-releasing hormone
    • Progonadoliberin II
    • cGnRH-II
  • Cleaved into 2 chains
    • Gonadoliberin-2 Alternative names: Gonadoliberin II, Gonadotropin-releasing hormone II (GnRH II) , Luliberin II, Luteinizing hormone-releasing hormone II (LH-RH II)
    • GnRH-associated peptide 2 Alternative names: GnRH-associated peptide II

Gene names

    • Name
      gnrh2

Organism names

  • Taxonomic identifier
  • Strains
    • Himedaka
    • HNI
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Beloniformes > Adrianichthyidae > Oryziinae > Oryzias

Accessions

  • Primary accession
    Q9DGC9
  • Secondary accessions
    • Q8JIQ5

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, modified residue, peptide, chain.

TypeIDPosition(s)Description
Signal1-21
Modified residue22Pyrrolidone carboxylic acid
PeptidePRO_000001249122-31Gonadoliberin-2
ChainPRO_000001249022-80Progonadoliberin-2
Modified residue31Glycine amide
PeptidePRO_000001249235-80GnRH-associated peptide 2

Keywords

Expression

Tissue specificity

Expressed in the cell bodies of a cluster of neurons in the midbrain tegmentum.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the GnRH family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    80
  • Mass (Da)
    9,311
  • Last updated
    2001-03-01 v1
  • Checksum
    CAE8F1B06B9AF26E
MSRLVLLLGVLLYVGAQLSQAQHWSHGWYPGGKRELDSFEVSEEMKLCETGECSYMRPQRRSFLRNIVLDALARELQKRK

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict50in Ref. 2; BAC06423
Sequence conflict55in Ref. 2; BAC06423
Sequence conflict62in Ref. 2; BAC06423
Sequence conflict71in Ref. 2; BAC06423

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB041330
EMBL· GenBank· DDBJ
BAB16300.1
EMBL· GenBank· DDBJ
mRNA
AB041334
EMBL· GenBank· DDBJ
BAC06417.1
EMBL· GenBank· DDBJ
Genomic DNA
AB074500
EMBL· GenBank· DDBJ
BAC06423.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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