Q9D638 · KRA32_MOUSE

  • Protein
    Keratin-associated protein 3-2
  • Gene
    Krtap3-2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentkeratin filament
Molecular Functionstructural molecule activity

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Keratin-associated protein 3-2
  • Alternative names
    • Keratin-associated protein 3-3

Gene names

    • Name
      Krtap3-2
    • Synonyms
      Krtap3-3

Organism names

  • Taxonomic identifier
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9D638
  • Secondary accessions
    • Q9CPW1

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylalanine
ChainPRO_00003585952-99Keratin-associated protein 3-2

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Interacts with hair keratins.

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for repeat, region.

TypeIDPosition(s)Description
Repeat3-71
Region3-593 X 5 AA repeats of C-C-X3
Repeat8-122
Repeat47-513

Sequence similarities

Belongs to the KRTAP type 3 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    99
  • Mass (Da)
    10,574
  • Last updated
    2008-12-16 v2
  • Checksum
    F0E5542FA890302B
MACCVARCCSVPTGPATTICSSDKSCRCGVCLPSTCPHTIWQLEPTCCDNCPPPCHIPQPCVPTCFLLNSCHPTPDLLTVNLTTYVQPGCEEPCVPRCC

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict13in Ref. 1; BAB29484

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK003615
EMBL· GenBank· DDBJ
BAB22891.1
EMBL· GenBank· DDBJ
mRNA
AK009410
EMBL· GenBank· DDBJ
BAB26270.1
EMBL· GenBank· DDBJ
mRNA
AK010142
EMBL· GenBank· DDBJ
BAB26727.1
EMBL· GenBank· DDBJ
mRNA
AK014641
EMBL· GenBank· DDBJ
BAB29484.1
EMBL· GenBank· DDBJ
mRNA
AL591417
EMBL· GenBank· DDBJ
CAM19193.1
EMBL· GenBank· DDBJ
Genomic DNA
AL591417
EMBL· GenBank· DDBJ
CAM19194.1
EMBL· GenBank· DDBJ
Genomic DNA
BC117058
EMBL· GenBank· DDBJ
AAI17059.1
EMBL· GenBank· DDBJ
mRNA
BC117092
EMBL· GenBank· DDBJ
AAI17093.1
EMBL· GenBank· DDBJ
mRNA
BC120760
EMBL· GenBank· DDBJ
AAI20761.1
EMBL· GenBank· DDBJ
mRNA
BC120762
EMBL· GenBank· DDBJ
AAI20763.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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