Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol- 3,5-bisphosphate.Yordanov T.E., Hipolito V.E.B., Liebscher G., Vogel G.F., Stasyk T., Herrmann C., Geley S., Teis D., Botelho R.J.[...], Huber L.A.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 1913689PubMedEurope PMCTraffic 20:674-696 (2019)Mapped to23
A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice.Snouwaert J.N., Church R.J., Jania L., Nguyen M., Wheeler M.L., Saintsing A., Mieczkowski P., Manuel de Villena F.P., Armao D.[...], Koller B.H.View abstractAnnotationTruncated Borcs7 reduces lysosomal transport in neurons and causes progressive axonal dystrophy.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 66439, MGI: 1913689PubMedEurope PMCCell Rep 24:1254-1265 (2018)Mapped to5