Q9CQA9 · NTPCR_MOUSE
- ProteinCancer-related nucleoside-triphosphatase homolog
- GeneNtpcr
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids190 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency.
Catalytic activity
- a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H+This reaction proceeds in the forward direction.
- TTP + H2O = TDP + phosphate + H+This reaction proceeds in the forward direction.
- CTP + H2O = CDP + phosphate + H+This reaction proceeds in the forward direction.
- ATP + H2O = ADP + phosphate + H+This reaction proceeds in the forward direction.
- GTP + H2O = GDP + phosphate + H+This reaction proceeds in the forward direction.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 9-16 | ATP (UniProtKB | ChEBI) | |||
Binding site | 109-116 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | CTPase activity | |
Molecular Function | GTPase activity | |
Molecular Function | ribonucleoside triphosphate phosphatase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCancer-related nucleoside-triphosphatase homolog
- EC number
- Short namesNTPase
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ9CQA9
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000146712 | 1-190 | Cancer-related nucleoside-triphosphatase homolog | ||
Modified residue | 165 | N6-acetyllysine | |||
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length190
- Mass (Da)20,667
- Last updated2001-06-01 v1
- ChecksumA6B9C6DFDFB06813
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK006433 EMBL· GenBank· DDBJ | BAB24586.1 EMBL· GenBank· DDBJ | mRNA | ||
AK010229 EMBL· GenBank· DDBJ | BAB26783.1 EMBL· GenBank· DDBJ | mRNA | ||
AK010823 EMBL· GenBank· DDBJ | BAB27206.1 EMBL· GenBank· DDBJ | mRNA | ||
AK019321 EMBL· GenBank· DDBJ | BAB31665.1 EMBL· GenBank· DDBJ | mRNA | ||
BC025168 EMBL· GenBank· DDBJ | AAH25168.1 EMBL· GenBank· DDBJ | mRNA |