Q9CQ61 · UNC50_MOUSE

  • Protein
    Protein unc-50 homolog
  • Gene
    Unc50
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Involved in the cell surface expression of neuronal nicotinic receptors (By similarity).
Binds RNA (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi membrane
Cellular Componentnuclear inner membrane
Molecular FunctionRNA binding
Biological Processprotein localization to cell surface

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein unc-50 homolog
  • Alternative names
    • Periodontal ligament-specific protein 22 (PDLs22)

Gene names

    • Name
      Unc50

Organism names

  • Taxonomic identifier
  • Strains
    • C57BL/6J
    • FVB/N
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9CQ61

Proteomes

Organism-specific databases

Subcellular Location

Nucleus inner membrane
; Multi-pass membrane protein
Golgi apparatus membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-82Cytoplasmic
Transmembrane83-103Helical
Topological domain104-112Lumenal
Transmembrane113-133Helical
Topological domain134-163Cytoplasmic
Transmembrane164-184Helical
Topological domain185-187Lumenal
Transmembrane188-208Helical
Topological domain209-222Cytoplasmic
Transmembrane223-243Helical
Topological domain244-259Lumenal

Keywords

PTM/Processing

Features

Showing features for modified residue, chain.

TypeIDPosition(s)Description
Modified residue1N-acetylmethionine
ChainPRO_00003089621-259Protein unc-50 homolog
Modified residue6Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Highly expressed in periodontal ligament and bone marrow, but not in gingival fibroblasts.

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Sequence similarities

Belongs to the unc-50 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    259
  • Mass (Da)
    30,429
  • Last updated
    2001-06-01 v1
  • Checksum
    C11FD3CD95FBD4A6
MLPSTSLSSSMHGNGVLNSRDAARHTAGAKRYKYLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKLLLWVVFIDCVGVGLLISTLMWFVSNKYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILTDTFIGYLVGNTLWLIAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLMVLYGLSLALGWNFTHTLCSFYKYRVK

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0A6YWQ8A0A0A6YWQ8_MOUSEUnc5086
A0A0A6YX35A0A0A6YX35_MOUSEUnc50170
D3YXX4D3YXX4_MOUSEUnc50214

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY017214
EMBL· GenBank· DDBJ
AAK08986.1
EMBL· GenBank· DDBJ
mRNA
AK003273
EMBL· GenBank· DDBJ
BAB22683.1
EMBL· GenBank· DDBJ
mRNA
AK004433
EMBL· GenBank· DDBJ
BAB23302.1
EMBL· GenBank· DDBJ
mRNA
AK132757
EMBL· GenBank· DDBJ
BAE21338.1
EMBL· GenBank· DDBJ
mRNA
AK135885
EMBL· GenBank· DDBJ
BAE22715.1
EMBL· GenBank· DDBJ
mRNA
BC019484
EMBL· GenBank· DDBJ
AAH19484.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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