Q9CAL8 · PEK13_ARATH
- ProteinProline-rich receptor-like protein kinase PERK13
- GenePERK13
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids710 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Negatively regulates root hair elongation.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | protein kinase binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProline-rich receptor-like protein kinase PERK13
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9CAL8
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-235 | Extracellular | ||||
Sequence: MSDSPTSSPPAPSADSAPPPDTSSDGSAAPPPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQGGPKKPKKHHPGPATSPPAPSAPATSPPAPPNAPPRNSSHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPANSGGGYQGKT | ||||||
Transmembrane | 236-256 | Helical | ||||
Sequence: MAGFAIAGFAVIALMAVVFLV | ||||||
Topological domain | 257-710 | Cytoplasmic | ||||
Sequence: RRKKKRNIDAYSDSQYLPPSNFSIKSDGFLYGQNPTKGYSGPGGYNSQQQSNSGNSFGSQRGGGGYTRSGSAPDSAVMGSGQTHFTYEELTDITEGFSKHNILGEGGFGCVYKGKLNDGKLVAVKQLKVGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVVRALDSEGDMGDISNGNKVGQSSAYDSGQYNNDTMKFRKMAFGFDDSSDSGMYSGDYSVQDSRKGSNGASSEFTRNETENRNFNNRRY |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Longer root hairs.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 46 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, glycosylation, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000400065 | 1-710 | Proline-rich receptor-like protein kinase PERK13 | |||
Sequence: MSDSPTSSPPAPSADSAPPPDTSSDGSAAPPPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQGGPKKPKKHHPGPATSPPAPSAPATSPPAPPNAPPRNSSHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPANSGGGYQGKTMAGFAIAGFAVIALMAVVFLVRRKKKRNIDAYSDSQYLPPSNFSIKSDGFLYGQNPTKGYSGPGGYNSQQQSNSGNSFGSQRGGGGYTRSGSAPDSAVMGSGQTHFTYEELTDITEGFSKHNILGEGGFGCVYKGKLNDGKLVAVKQLKVGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVVRALDSEGDMGDISNGNKVGQSSAYDSGQYNNDTMKFRKMAFGFDDSSDSGMYSGDYSVQDSRKGSNGASSEFTRNETENRNFNNRRY | ||||||
Glycosylation | 191 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Modified residue | 342 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 426 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 510 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 511 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 516 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 524 | Phosphotyrosine | ||||
Sequence: Y |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Mostly expressed in roots, especially in root hairs.
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-229 | Disordered | ||||
Sequence: MSDSPTSSPPAPSADSAPPPDTSSDGSAAPPPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQGGPKKPKKHHPGPATSPPAPSAPATSPPAPPNAPPRNSSHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPANSGG | ||||||
Compositional bias | 31-155 | Pro residues | ||||
Sequence: PPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQG | ||||||
Compositional bias | 166-192 | Pro residues | ||||
Sequence: GPATSPPAPSAPATSPPAPPNAPPRNS | ||||||
Compositional bias | 193-226 | Polar residues | ||||
Sequence: SHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPAN | ||||||
Region | 289-334 | Disordered | ||||
Sequence: QNPTKGYSGPGGYNSQQQSNSGNSFGSQRGGGGYTRSGSAPDSAVM | ||||||
Compositional bias | 295-322 | Polar residues | ||||
Sequence: YSGPGGYNSQQQSNSGNSFGSQRGGGGY | ||||||
Domain | 353-619 | Protein kinase | ||||
Sequence: FSKHNILGEGGFGCVYKGKLNDGKLVAVKQLKVGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRM | ||||||
Compositional bias | 676-700 | Polar residues | ||||
Sequence: SGDYSVQDSRKGSNGASSEFTRNET | ||||||
Region | 676-710 | Disordered | ||||
Sequence: SGDYSVQDSRKGSNGASSEFTRNETENRNFNNRRY |
Sequence similarities
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length710
- Mass (Da)75,372
- Last updated2001-06-01 v1
- Checksum8B4420A8DD8F3AA6
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 31-155 | Pro residues | ||||
Sequence: PPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQG | ||||||
Sequence conflict | 67 | in Ref. 3; BX816903 | ||||
Sequence: S → A | ||||||
Sequence conflict | 83-84 | in Ref. 3; BX816903 | ||||
Sequence: LT → FC | ||||||
Compositional bias | 166-192 | Pro residues | ||||
Sequence: GPATSPPAPSAPATSPPAPPNAPPRNS | ||||||
Sequence conflict | 174 | in Ref. 3; BX816903 | ||||
Sequence: P → L | ||||||
Compositional bias | 193-226 | Polar residues | ||||
Sequence: SHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPAN | ||||||
Compositional bias | 295-322 | Polar residues | ||||
Sequence: YSGPGGYNSQQQSNSGNSFGSQRGGGGY | ||||||
Compositional bias | 676-700 | Polar residues | ||||
Sequence: SGDYSVQDSRKGSNGASSEFTRNET |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC010796 EMBL· GenBank· DDBJ | AAG52479.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE35064.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BX816903 EMBL· GenBank· DDBJ | - | mRNA | No translation available. |