Q9CAG3 · LOX6_ARATH
- ProteinLipoxygenase 6, chloroplastic
- GeneLOX6
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids917 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).
13S-lipoxygenase that can use linolenic acid as substrates
13S-lipoxygenase that can use linolenic acid as substrates
Catalytic activity
- (9Z,12Z)-octadecadienoate + O2 = (13S)-hydroperoxy-(9Z,11E)-octadecadienoate
Cofactor
Note: Binds 1 Fe cation per subunit.
Pathway
Lipid metabolism; oxylipin biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 575 | Fe cation (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 580 | Fe cation (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 767 | Fe cation (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 771 | Fe cation (UniProtKB | ChEBI); catalytic | ||||
Sequence: N | ||||||
Binding site | 917 | Fe cation (UniProtKB | ChEBI); catalytic | ||||
Sequence: I |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Cellular Component | plasma membrane | |
Molecular Function | linoleate 13S-lipoxygenase activity | |
Molecular Function | metal ion binding | |
Biological Process | jasmonic acid biosynthetic process | |
Biological Process | lipid oxidation | |
Biological Process | oxylipin biosynthetic process | |
Biological Process | response to wounding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLipoxygenase 6, chloroplastic
- EC number
- Short namesAtLOX6
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9CAG3
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-40 | Chloroplast | ||||
Sequence: MFVASPVKTNFNGVSLVKSPAFSALSCRKQHRVPISRQVR | ||||||
Chain | PRO_0000380595 | 41-917 | Lipoxygenase 6, chloroplastic | |||
Sequence: AVISREEKAVDQEDGKKSTNKPLINSSQFPWQRSKYTGSKTVTAVVKIRKKIKEKLTERFEHQLELFMKAIGQGMLIQLVSEEIDPETGKGRKSLESPVMGLPKAVKDPRYLVFTADFTVPINFGKPGAILVTNLLSTEICLSEIIIEDSTDTILFPANTWIHSKNDNPQARIIFRSQPCLPSETPDGIKELREKDLVSVRGDGKGERKPHERIYDYDVYNDLGDPRKTERVRPVLGVPETPYPRRCRTGRPLVSKDPPCESRGKEKEEFYVPRDEVFEEIKRDTFRAGRFKALFHNLVPSIAAALSNLDIPFTCFSDIDNLYKSNIVLGHTEPKDTGLGGFIGGFMNGILNVTETLLKYDTPAVIKWDRFAWLRDNEFGRQALAGVNPVNIELLKELPIRSNLDPALYGPQESVLTEEIIAREVEHYGTTIEKALEEKRLFLVDYHDILLPFVEKINSIKEDPRKTYASRTIFFYSKNGALRPLAIELSLPPTAESENKFVYTHGHDATTHWIWKLAKAHVCSNDAGVHQLVNHWLRTHASMEPYIIATNRQLSTMHPVYKLLHPHMRYTLEINARARKSLINGGGIIESCFTPGKYAMELSSAAYKSMWRFDMEGLPADLVRRGMAEEDSSAECGVRLVIDDYPYAADGLLIWKAIKDLVESYVKHFYSDSKSITSDLELQAWWDEIKNKGHYDKKDEPWWPKLNTTQDLSQILTNMIWIASGQHAAINFGQYPFGGYVPNRPTLLRKLIPQETDPDYEMFMRNPQYSFLGSLPTQLQATKVMAVQETLSTHSPDEEYLIELREVQRHWFQDEQVVKYFNKFSEELVKIEKTINERNKDKKLKNRTGAGMPPYELLLPTSPHGVTGRGIPNSISI |
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 46-66 | Disordered | ||||
Sequence: EEKAVDQEDGKKSTNKPLINS | ||||||
Domain | 98-216 | PLAT | ||||
Sequence: ERFEHQLELFMKAIGQGMLIQLVSEEIDPETGKGRKSLESPVMGLPKAVKDPRYLVFTADFTVPINFGKPGAILVTNLLSTEICLSEIIIEDSTDTILFPANTWIHSKNDNPQARIIFR | ||||||
Domain | 219-917 | Lipoxygenase | ||||
Sequence: PCLPSETPDGIKELREKDLVSVRGDGKGERKPHERIYDYDVYNDLGDPRKTERVRPVLGVPETPYPRRCRTGRPLVSKDPPCESRGKEKEEFYVPRDEVFEEIKRDTFRAGRFKALFHNLVPSIAAALSNLDIPFTCFSDIDNLYKSNIVLGHTEPKDTGLGGFIGGFMNGILNVTETLLKYDTPAVIKWDRFAWLRDNEFGRQALAGVNPVNIELLKELPIRSNLDPALYGPQESVLTEEIIAREVEHYGTTIEKALEEKRLFLVDYHDILLPFVEKINSIKEDPRKTYASRTIFFYSKNGALRPLAIELSLPPTAESENKFVYTHGHDATTHWIWKLAKAHVCSNDAGVHQLVNHWLRTHASMEPYIIATNRQLSTMHPVYKLLHPHMRYTLEINARARKSLINGGGIIESCFTPGKYAMELSSAAYKSMWRFDMEGLPADLVRRGMAEEDSSAECGVRLVIDDYPYAADGLLIWKAIKDLVESYVKHFYSDSKSITSDLELQAWWDEIKNKGHYDKKDEPWWPKLNTTQDLSQILTNMIWIASGQHAAINFGQYPFGGYVPNRPTLLRKLIPQETDPDYEMFMRNPQYSFLGSLPTQLQATKVMAVQETLSTHSPDEEYLIELREVQRHWFQDEQVVKYFNKFSEELVKIEKTINERNKDKKLKNRTGAGMPPYELLLPTSPHGVTGRGIPNSISI | ||||||
Region | 880-904 | Disordered | ||||
Sequence: KDKKLKNRTGAGMPPYELLLPTSPH |
Sequence similarities
Belongs to the lipoxygenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length917
- Mass (Da)104,516
- Last updated2001-06-01 v1
- Checksum14405AD036EC3F64
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ748537 EMBL· GenBank· DDBJ | CAG38328.1 EMBL· GenBank· DDBJ | mRNA | ||
AC011020 EMBL· GenBank· DDBJ | AAG52309.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE34664.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY081253 EMBL· GenBank· DDBJ | AAL91142.1 EMBL· GenBank· DDBJ | mRNA | ||
BT010546 EMBL· GenBank· DDBJ | AAQ65169.1 EMBL· GenBank· DDBJ | mRNA | ||
AK222124 EMBL· GenBank· DDBJ | BAD95111.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AK230188 EMBL· GenBank· DDBJ | BAF01997.1 EMBL· GenBank· DDBJ | mRNA |