Q9C8H0 · AB12C_ARATH
- ProteinABC transporter C family member 12
- GeneABCC12
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1495 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Pump for glutathione S-conjugates.
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 650-657 | ATP 1 (UniProtKB | ChEBI) | |||
Binding site | 1269-1276 | ATP 2 (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | ABC-type xenobiotic transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATPase-coupled transmembrane transporter activity | |
Biological Process | transmembrane transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameABC transporter C family member 12
- EC number
- Short namesABC transporter ABCC.12; AtABCC12
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9C8H0
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 38-58 | Helical | |||
Transmembrane | 76-96 | Helical | |||
Transmembrane | 110-130 | Helical | |||
Transmembrane | 146-166 | Helical | |||
Transmembrane | 173-195 | Helical | |||
Transmembrane | 303-323 | Helical | |||
Transmembrane | 337-357 | Helical | |||
Transmembrane | 420-440 | Helical | |||
Transmembrane | 441-461 | Helical | |||
Transmembrane | 528-548 | Helical | |||
Transmembrane | 558-578 | Helical | |||
Transmembrane | 907-927 | Helical | |||
Transmembrane | 949-969 | Helical | |||
Transmembrane | 1042-1062 | Helical | |||
Transmembrane | 1140-1160 | Helical | |||
Transmembrane | 1166-1186 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000226084 | 1-1495 | ABC transporter C family member 12 | ||
Proteomic databases
Expression
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 303-583 | ABC transmembrane type-1 1 | |||
Domain | 615-839 | ABC transporter 1 | |||
Domain | 914-1198 | ABC transmembrane type-1 2 | |||
Domain | 1235-1469 | ABC transporter 2 | |||
Sequence similarities
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,495
- Mass (Da)167,956
- Last updated2001-06-01 v1
- MD5 Checksum362A93E615E05B7FD385193AC4517473
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8AW42 | A0A1P8AW42_ARATH | ABCC12 | 1380 | ||
A0A1P8AW56 | A0A1P8AW56_ARATH | ABCC12 | 1365 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC025295 EMBL· GenBank· DDBJ | AAG51100.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | ANM60872.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | ANM60873.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | ANM60875.1 EMBL· GenBank· DDBJ | Genomic DNA |