Q9C826 · ABA2_ARATH

Function

function

Involved in the biosynthesis of abscisic acid (PubMed:10972885, PubMed:12172025, PubMed:12417697, PubMed:9159947).
Catalyzes the conversion of xanthoxin to abscisic aldehyde (PubMed:12172025, PubMed:12417697, PubMed:9159947).

Miscellaneous

The biological substrate is probably 2-cis,4-trans-xanthoxin.

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
19 μMxanthoxin
10 mM3,5,5'-trimethylcyclohexanol
no activity with xanthoxic acid, ethanol, isopropanol, butanol, cyclohexanol and 2,6-dimethylcyclohexanol.

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentnucleus
Molecular Functionalcohol dehydrogenase (NAD+) activity
Molecular Functionidentical protein binding
Molecular Functionxanthoxin dehydrogenase (NAD+) activity
Biological Processabscisic acid biosynthetic process
Biological Processproline biosynthetic process
Biological Processregulation of abscisic acid biosynthetic process
Biological Processresponse to fructose
Biological Processresponse to heat
Biological Processresponse to water deprivation
Biological Processsugar mediated signaling pathway

Keywords

Enzyme and pathway databases

Chemistry

Names & Taxonomy

Protein names

  • Recommended name
    Xanthoxin dehydrogenase
  • EC number
  • Alternative names
    • Protein ABSCISIC ACID DEFICIENT 2
    • Protein GLUCOSE INSENSITIVE 1
    • Protein IMPAIRED SUCROSE INDUCTION 4
    • Protein SALOBRENO 3
    • Protein SALT RESISTANT 1

Gene names

    • Name
      ABA2
    • Synonyms
      GIN1
      , ISI4
      , SAN3
      , SDR1
      , SIS4
      , SRE1
    • ORF names
      F19K6.3
    • Ordered locus names
      At1g52340

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9C826

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis28In aba2-12/sre1-2; reduced absicic acid synthesis.
Mutagenesis45In aba2-4/sis4-2; reduced absicic acid synthesis.
Mutagenesis145In gin1-2; reduced absicic acid synthesis.
Mutagenesis162In aba2-3/sis4-1; reduced absicic acid synthesis.
Mutagenesis176In aba2-13/san3-1; reduced absicic acid synthesis.
Mutagenesis236In isi4; reduced absicic acid synthesis.
Mutagenesis264In aba2-1; reduced absicic acid synthesis.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 24 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylserine
ChainPRO_00002823472-285Xanthoxin dehydrogenase

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Predominantly in roots and stems, and at lower levels in leaves and seeds.

Induction

Constitutively expressed and not up regulated by osmotic stress.

Gene expression databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q9C826ABA2 Q9C8266EBI-4464299, EBI-4464299
BINARY Q9C826ABCI10 Q8H1R43EBI-4464299, EBI-17091580

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    285
  • Mass (Da)
    30,272
  • Last updated
    2001-06-01 v1
  • Checksum
    8B555DAED7386DF4
MSTNTESSSYSSLPSQRLLGKVALITGGATGIGESIVRLFHKHGAKVCIVDLQDDLGGEVCKSLLRGESKETAFFIHGDVRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIRNYSLSEFEMTFDVNVKGAFLSMKHAARVMIPEKKGSIVSLCSVGGVVGGVGPHSYVGSKHAVLGLTRSVAAELGQHGIRVNCVSPYAVATKLALAHLPEEERTEDAFVGFRNFAAANANLKGVELTVDDVANAVLFLASDDSRYISGDNLMIDGGFTCTNHSFKVFR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC037424
EMBL· GenBank· DDBJ
AAG51536.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE32789.1
EMBL· GenBank· DDBJ
Genomic DNA
BT003412
EMBL· GenBank· DDBJ
AAO30075.1
EMBL· GenBank· DDBJ
mRNA
AY099603
EMBL· GenBank· DDBJ
AAM20454.1
EMBL· GenBank· DDBJ
mRNA
AY082344
EMBL· GenBank· DDBJ
AAL99237.1
EMBL· GenBank· DDBJ
mRNA
AY082345
EMBL· GenBank· DDBJ
AAL99238.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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