Q9C7Z1 · G2OX4_ARATH
- ProteinGibberellin 2-beta-dioxygenase 4
- GeneGA2OX4
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids321 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development. Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8.
Catalytic activity
- gibberellin A1 + 2-oxoglutarate + O2 = gibberellin A8 + succinate + CO2
Cofactor
Note: Binds 1 Fe2+ ion per subunit.
Pathway
Plant hormone biosynthesis; gibberellin biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 193 | Fe cation (UniProtKB | ChEBI) | |||
Binding site | 195 | Fe cation (UniProtKB | ChEBI) | |||
Binding site | 250 | Fe cation (UniProtKB | ChEBI) | |||
Active site | 260 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | C-19 gibberellin 2-beta-dioxygenase activity | |
Molecular Function | metal ion binding | |
Biological Process | gibberellin biosynthetic process | |
Biological Process | gibberellin catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGibberellin 2-beta-dioxygenase 4
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9C7Z1
Proteomes
Organism-specific databases
Genome annotation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000422355 | 1-321 | Gibberellin 2-beta-dioxygenase 4 | ||
Proteomic databases
Expression
Tissue specificity
Expressed at the base of the shoot apical meristem and developing leaf primordia.
Induction
Not regulated by auxin. Down-regulated by paclobutrazol.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 156-269 | Fe2OG dioxygenase | |||
Sequence similarities
Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length321
- Mass (Da)35,873
- Last updated2001-06-01 v1
- Checksum2802A9CE2B30C973
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY859740 EMBL· GenBank· DDBJ | AAW56769.1 EMBL· GenBank· DDBJ | mRNA | ||
AC051631 EMBL· GenBank· DDBJ | AAG51528.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE32235.1 EMBL· GenBank· DDBJ | Genomic DNA |