Q9C6T1 · PMK_ARATH

Function

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
11.8 μM(R)-5-phosphomevalonate
kcat is 20.9 sec-1 with (R)-5-phosphomevalonate.

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 2/3.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site177-187ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular FunctionATP binding
Molecular Functionphosphomevalonate kinase activity
Biological Processisopentenyl diphosphate biosynthetic process, mevalonate pathway
Biological Processphosphorylation
Biological Processsterol biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomevalonate kinase, peroxisomal
  • EC number
  • Alternative names
    • 5-phosphomevalonate kinase
      (AtPMK
      )

Gene names

    • Name
      PMK
    • ORF names
      F5M6.9
    • Ordered locus names
      At1g31910

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9C6T1
  • Secondary accessions
    • Q681V6
    • Q682Q9

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain.

Type
IDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylalanine
ChainPRO_00004356092-505Phosphomevalonate kinase, peroxisomal

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif57-65Peroxisomal targeting signal PTS2

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q9C6T1-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    505
  • Mass (Da)
    54,409
  • Last updated
    2001-06-01 v1
  • Checksum
    B1CBA6CA338B3D63
MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPINEEVKPESWAWKWTDVKLTSPQLSRESMYKLSLNHLTLQSVSASDSRNPFVEHAIQYAIAAAHLATEKDKESLHKLLLQGLDITILGSNDFYSYRNQIESAGLPLTPESLGTLAPFASITFNAAESNGANSKPEVAKTGLGSSAAMTTAVVAALLHYLGVVDLSDPCKEGKFGCSDLDVIHMIAQTSHCLAQGKVGSGFDVSCAVYGSQRYVRFSPEVLSFAQVAVTGLPLNEVIGTILKGKWDNKRTEFSLPPLMNLFLGEPGSGGSSTPSMVGAVKKWQMSDPEKARENWQNLSDANLELETKLNDLSKLAKDHWDVYLRVIKSCSVLTSEKWVLHATEPINEAIIKELLEAREAMLRIRILMRQMGEAASVPIEPESQTQLLDSTMSAEGVLLAGVPGAGGFDAIFAITLGDSGTKLTQAWSSHNVLALLVREDPHGVCLESGDPRTTCITSGVSSIHLE

Q9C6T1-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 418-450: IEPESQTQLLDSTMSAEGVLLAGVPGAGGFDAI → NLNSIHDIRVPQIPHLEQIDFIIIDLEGPWNCR
    • 451-505: Missing

Features

Showing features for sequence conflict, alternative sequence.

Type
IDPosition(s)Description
Sequence conflict44in Ref. 3; BAD43274
Sequence conflict54in Ref. 3; BAD43274
Alternative sequenceVSP_058117418-450in isoform 2
Alternative sequenceVSP_058118451-505in isoform 2

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC079041
EMBL· GenBank· DDBJ
AAG50716.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE31414.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE31415.1
EMBL· GenBank· DDBJ
Genomic DNA
AK175299
EMBL· GenBank· DDBJ
BAD43062.1
EMBL· GenBank· DDBJ
mRNA
AK175308
EMBL· GenBank· DDBJ
BAD43071.1
EMBL· GenBank· DDBJ
mRNA
AK175511
EMBL· GenBank· DDBJ
BAD43274.1
EMBL· GenBank· DDBJ
mRNA
AK176723
EMBL· GenBank· DDBJ
BAD44486.1
EMBL· GenBank· DDBJ
mRNA
AK176889
EMBL· GenBank· DDBJ
BAD44652.1
EMBL· GenBank· DDBJ
mRNA
AK221797
EMBL· GenBank· DDBJ
BAD93949.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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