Q9C5W7 · TOM2A_ARATH

Function

function

Necessary for the efficient intracellular multiplication of tobamoviruses, being a component of the replication complex.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentGolgi apparatus
Cellular Componentmembrane
Cellular Componentnucleus
Cellular Componentplant-type vacuole
Cellular Componentplant-type vacuole membrane
Cellular Componentplasmodesma
Biological Processviral replication complex formation and maintenance

Names & Taxonomy

Protein names

  • Recommended name
    Tobamovirus multiplication protein 2A
  • Short names
    AtTOM2A

Gene names

    • Name
      TOM2A
    • ORF names
      F5D14.22
    • Ordered locus names
      At1g32400

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9C5W7
  • Secondary accessions
    • Q56Z79
    • Q9LQL8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-13Cytoplasmic
Transmembrane14-34Helical
Topological domain35-78Extracellular
Transmembrane79-99Helical
Topological domain100-113Cytoplasmic
Transmembrane114-134Helical
Topological domain135-162Extracellular
Transmembrane163-183Helical
Topological domain184-280Cytoplasmic

Keywords

Phenotypes & Variants

Disruption phenotype

Reduced efficiency of intracellular multiplication of tobamoviruses (e.g. crucifer strain TMV-Cg), characterized by a reduced amplification of TMV-related RNAs.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 24 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00004236741-280Tobamovirus multiplication protein 2A
Modified residue196Phosphoserine
Modified residue233Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in rosette leaves.

Gene expression databases

Interaction

Subunit

Homodimer. Constituent of tobamovirus replication complex. Interacts with TOM1.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region258-280Disordered

Sequence similarities

Belongs to the tetraspanin (TM4SF) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    280
  • Mass (Da)
    31,556
  • Last updated
    2001-06-01 v1
  • Checksum
    227C8FE0658A8C0C
MACRGCLECLLKLLNFLLAVAGLGMIGYGIYLFVEYKRVTDNSVTFDLTNGDQSYVSFGRPILMAVSLSSNIFDNLPKAWFIYLFIGIGVALFVISCCGCVGTCSRSVCCLSCYSLLLILLILVELGFAAFIFFDNSWRDELPSDRTGNFDTIYNFLRENWKIVRWVALGAVVFEALLFLLALMVRAANTPAEYDSDDEYLAPRQQIRQPFINRQAAPVTGVPVAPTLDQRPSRSDPWSARMREKYGLDTSEFTYNPSESHRFQQMPAQPNEEKGRCTIM

Sequence caution

The sequence AAF81337.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB085684
EMBL· GenBank· DDBJ
BAC24019.1
EMBL· GenBank· DDBJ
mRNA
AC007767
EMBL· GenBank· DDBJ
AAF81337.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002684
EMBL· GenBank· DDBJ
AEE31476.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE31477.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE31478.1
EMBL· GenBank· DDBJ
Genomic DNA
AF334723
EMBL· GenBank· DDBJ
AAG50101.1
EMBL· GenBank· DDBJ
mRNA
AF385687
EMBL· GenBank· DDBJ
AAK60280.1
EMBL· GenBank· DDBJ
mRNA
AY088560
EMBL· GenBank· DDBJ
AAM66092.1
EMBL· GenBank· DDBJ
mRNA
AK221090
EMBL· GenBank· DDBJ
BAD94952.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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