Q9C5J6 · IPT9_ARATH
- ProteintRNA dimethylallyltransferase 9
- GeneIPT9
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids463 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A). Involved in the cis-type cytokinin biosynthesis.
Catalytic activity
- adenosine37 in tRNA + dimethylallyl diphosphate = N6-dimethylallyladenosine37 in tRNA + diphosphate
Cofactor
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 57-64 | ATP (UniProtKB | ChEBI) | |||
Binding site | 59-64 | substrate | |||
Site | 148 | Interaction with substrate tRNA | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | tRNA dimethylallyltransferase activity | |
Biological Process | cytokinin biosynthetic process | |
Biological Process | tRNA modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA dimethylallyltransferase 9
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9C5J6
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
No visible phenotype, due the redundancy with IPT2. Often chlorotic.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 28 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000391077 | 1-463 | tRNA dimethylallyltransferase 9 | ||
Proteomic databases
Expression
Tissue specificity
Expressed ubiquitously, with highest expression in proliferating tissues.
Induction
Not regulated by cytokinin, auxin or nitrate.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q9C5J6-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length463
- Mass (Da)52,264
- Last updated2001-06-01 v1
- ChecksumA36E0736B56DF50C
Q9C5J6-2
- Name2
- Differences from canonical
- 431-434: Missing
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F4K2Q7 | F4K2Q7_ARATH | IPT9 | 469 |
Features
Showing features for sequence conflict, alternative sequence.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 121 | in Ref. 5; AAM63091 | |||
Alternative sequence | VSP_038685 | 431-434 | in isoform 2 | ||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB062615 EMBL· GenBank· DDBJ | BAB59048.1 EMBL· GenBank· DDBJ | mRNA | ||
AF296836 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CP002688 EMBL· GenBank· DDBJ | AED92782.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED92783.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF360208 EMBL· GenBank· DDBJ | AAK25918.1 EMBL· GenBank· DDBJ | mRNA | ||
AY040056 EMBL· GenBank· DDBJ | AAK64114.1 EMBL· GenBank· DDBJ | mRNA | ||
AY085878 EMBL· GenBank· DDBJ | AAM63091.1 EMBL· GenBank· DDBJ | mRNA |