Q9BE72 · GTR12_MACFA

Function

function

Insulin-independent facilitative glucose transporter.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendomembrane system
Cellular Componentperinuclear region of cytoplasm
Cellular Componentplasma membrane
Molecular Functionglucose transmembrane transporter activity
Molecular Functionsymporter activity
Biological Processcirculatory system development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Solute carrier family 2, facilitated glucose transporter member 12
  • Alternative names
    • Glucose transporter type 12
      (GLUT-12
      )

Gene names

    • Name
      SLC2A12
    • Synonyms
      GLUT12
    • ORF names
      QflA-11110

Organism names

Accessions

  • Primary accession
    Q9BE72

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein
Note: Localizes primarily perinuclear region in the absence of insulin.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-48Cytoplasmic
Transmembrane49-69Helical
Topological domain70-84Extracellular
Transmembrane85-105Helical
Topological domain106-119Cytoplasmic
Transmembrane120-140Helical
Topological domain141Extracellular
Transmembrane142-162Helical
Topological domain163-176Cytoplasmic
Transmembrane177-197Helical
Topological domain198-201Extracellular
Transmembrane202-222Helical
Topological domain223-282Cytoplasmic
Transmembrane283-303Helical
Topological domain304-321Extracellular
Transmembrane322-342Helical
Topological domain343-349Cytoplasmic
Transmembrane350-370Helical
Topological domain371-470Extracellular
Transmembrane471-491Helical
Topological domain492-502Cytoplasmic
Transmembrane503-523Helical
Topological domain524-532Extracellular
Transmembrane533-553Helical
Topological domain554-621Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00002920151-621Solute carrier family 2, facilitated glucose transporter member 12
Glycosylation375N-linked (GlcNAc...) asparagine
Glycosylation387N-linked (GlcNAc...) asparagine
Glycosylation400N-linked (GlcNAc...) asparagine
Glycosylation405N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    621
  • Mass (Da)
    67,486
  • Last updated
    2001-06-01 v1
  • Checksum
    9E9384A2320AC716
MVPVENTEGPNLLNQKGTAVETEGSYRASGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLTLSCHEQEMVVSSLLIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGILQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDATEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTNICRSHNSINQSLDESVIYGPGNLSASNNTLRDHFKGIASHSRSSLMPLRNDVDKRGETTSASLLNAVLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPRQPQKRKPQEQLLECNKLCGRGQSRQLSPEN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB056798
EMBL· GenBank· DDBJ
BAB39322.1
EMBL· GenBank· DDBJ
mRNA

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