Q9B2Z1 · Q9B2Z1_HUMAN

  • Protein
    NADH-ubiquinone oxidoreductase chain 4L
  • Gene
    ND4L
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Part of the enzyme membrane arm which is embedded in the lipid bilayer and involved in proton translocation.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4L
  • EC number

Gene names

    • Name
      ND4L
    • Synonyms
      NADH4L

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 61
    • MTDNA505
    • GD7811
    • DCH002
    • ONsq0062
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q9B2Z1

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-22Helical
Transmembrane29-49Helical
Transmembrane55-79Helical

Keywords

PTM/Processing

Proteomic databases

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Structure

Family & Domains

Sequence similarities

Belongs to the complex I subunit 4L family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    98
  • Mass (Da)
    10,711
  • Last updated
    2001-06-01 v1
  • Checksum
    24B91F0E500676D2
MPLIYMNIMLAFTISLLGMLVYRSHLMSSLLCLEGMMLSLFIMATLTTLNTHSLLANIVPIAMLVFAACEAAVGLALLVSISNTYGLDYVHNLNLLQC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF346971
EMBL· GenBank· DDBJ
AAK17319.1
EMBL· GenBank· DDBJ
Genomic DNA
AY063376
EMBL· GenBank· DDBJ
AAL48358.1
EMBL· GenBank· DDBJ
Genomic DNA
AY255164
EMBL· GenBank· DDBJ
AAO67029.1
EMBL· GenBank· DDBJ
Genomic DNA
AY195791
EMBL· GenBank· DDBJ
AAO88886.1
EMBL· GenBank· DDBJ
Genomic DNA
AY289099
EMBL· GenBank· DDBJ
AAP48511.1
EMBL· GenBank· DDBJ
Genomic DNA
AY950289
EMBL· GenBank· DDBJ
AAX47805.2
EMBL· GenBank· DDBJ
Genomic DNA
AY963572
EMBL· GenBank· DDBJ
AAX53680.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ272124
EMBL· GenBank· DDBJ
ABB51471.1
EMBL· GenBank· DDBJ
Genomic DNA
EF114270
EMBL· GenBank· DDBJ
ABO36804.1
EMBL· GenBank· DDBJ
Genomic DNA
EF657682
EMBL· GenBank· DDBJ
ABR98832.1
EMBL· GenBank· DDBJ
Genomic DNA
EU007894
EMBL· GenBank· DDBJ
ABS58456.1
EMBL· GenBank· DDBJ
Genomic DNA
EU482358
EMBL· GenBank· DDBJ
ACA22587.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ198214
EMBL· GenBank· DDBJ
ACI04272.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ748713
EMBL· GenBank· DDBJ
ACN37241.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ770967
EMBL· GenBank· DDBJ
ACN49845.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ119028
EMBL· GenBank· DDBJ
ACS48839.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ301863
EMBL· GenBank· DDBJ
ACT15641.1
EMBL· GenBank· DDBJ
Genomic DNA
GU377084
EMBL· GenBank· DDBJ
ADB78181.1
EMBL· GenBank· DDBJ
Genomic DNA
HM357814
EMBL· GenBank· DDBJ
ADI79466.1
EMBL· GenBank· DDBJ
Genomic DNA
HM852794
EMBL· GenBank· DDBJ
ADL30396.1
EMBL· GenBank· DDBJ
Genomic DNA
HM596654
EMBL· GenBank· DDBJ
ADN10975.1
EMBL· GenBank· DDBJ
Genomic DNA
GU392054
EMBL· GenBank· DDBJ
ADN41765.1
EMBL· GenBank· DDBJ
Genomic DNA
GU733782
EMBL· GenBank· DDBJ
ADP23188.1
EMBL· GenBank· DDBJ
Genomic DNA
HM238199
EMBL· GenBank· DDBJ
ADV35182.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ700871
EMBL· GenBank· DDBJ
ADV38755.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ713444
EMBL· GenBank· DDBJ
ADW26255.1
EMBL· GenBank· DDBJ
Genomic DNA
JF739536
EMBL· GenBank· DDBJ
AEE60375.1
EMBL· GenBank· DDBJ
Genomic DNA
JF824884
EMBL· GenBank· DDBJ
AEG63048.1
EMBL· GenBank· DDBJ
Genomic DNA
JN133516
EMBL· GenBank· DDBJ
AEK66608.1
EMBL· GenBank· DDBJ
Genomic DNA
JQ702074
EMBL· GenBank· DDBJ
AFF64928.1
EMBL· GenBank· DDBJ
Genomic DNA
JX024566
EMBL· GenBank· DDBJ
AFK80783.1
EMBL· GenBank· DDBJ
Genomic DNA
JX153089
EMBL· GenBank· DDBJ
AFO24338.1
EMBL· GenBank· DDBJ
Genomic DNA
KC505083
EMBL· GenBank· DDBJ
AGI49755.1
EMBL· GenBank· DDBJ
Genomic DNA
KC733252
EMBL· GenBank· DDBJ
AGL11388.1
EMBL· GenBank· DDBJ
Genomic DNA
KC993912
EMBL· GenBank· DDBJ
AGO21849.1
EMBL· GenBank· DDBJ
Genomic DNA
KC911336
EMBL· GenBank· DDBJ
AGO91116.1
EMBL· GenBank· DDBJ
Genomic DNA
KF056261
EMBL· GenBank· DDBJ
AGT52588.1
EMBL· GenBank· DDBJ
Genomic DNA
KC252363
EMBL· GenBank· DDBJ
AGX90104.1
EMBL· GenBank· DDBJ
Genomic DNA
KF540547
EMBL· GenBank· DDBJ
AGZ06411.1
EMBL· GenBank· DDBJ
Genomic DNA
KF450880
EMBL· GenBank· DDBJ
AGZ65081.1
EMBL· GenBank· DDBJ
Genomic DNA
KF148087
EMBL· GenBank· DDBJ
AGZ95986.1
EMBL· GenBank· DDBJ
Genomic DNA
KF849920
EMBL· GenBank· DDBJ
AHE78856.1
EMBL· GenBank· DDBJ
Genomic DNA
KM101607
EMBL· GenBank· DDBJ
AIU57598.1
EMBL· GenBank· DDBJ
Genomic DNA
KP346026
EMBL· GenBank· DDBJ
AKC00071.1
EMBL· GenBank· DDBJ
Genomic DNA
KP340146
EMBL· GenBank· DDBJ
AKH35522.1
EMBL· GenBank· DDBJ
Genomic DNA
KU521498
EMBL· GenBank· DDBJ
AMK47588.1
EMBL· GenBank· DDBJ
Genomic DNA
KT725898
EMBL· GenBank· DDBJ
ANA92486.1
EMBL· GenBank· DDBJ
Genomic DNA
KX228162
EMBL· GenBank· DDBJ
ANP95058.1
EMBL· GenBank· DDBJ
Genomic DNA
KX456435
EMBL· GenBank· DDBJ
APD52693.1
EMBL· GenBank· DDBJ
Genomic DNA
KX675303
EMBL· GenBank· DDBJ
APZ83643.1
EMBL· GenBank· DDBJ
Genomic DNA
MF043438
EMBL· GenBank· DDBJ
ATP01695.1
EMBL· GenBank· DDBJ
Genomic DNA
MF695990
EMBL· GenBank· DDBJ
AUT78987.1
EMBL· GenBank· DDBJ
Genomic DNA
MG272585
EMBL· GenBank· DDBJ
AVL85033.1
EMBL· GenBank· DDBJ
Genomic DNA
MH359195
EMBL· GenBank· DDBJ
AWV63671.1
EMBL· GenBank· DDBJ
Genomic DNA
MH981651
EMBL· GenBank· DDBJ
AYV90675.1
EMBL· GenBank· DDBJ
Genomic DNA
MH448949
EMBL· GenBank· DDBJ
AYW04057.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008279
EMBL· GenBank· DDBJ
BAE07618.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008577
EMBL· GenBank· DDBJ
BAE11494.1
EMBL· GenBank· DDBJ
Genomic DNA
AP010664
EMBL· GenBank· DDBJ
BAG14440.1
EMBL· GenBank· DDBJ
Genomic DNA
AP009440
EMBL· GenBank· DDBJ
BAG38988.1
EMBL· GenBank· DDBJ
Genomic DNA
AP010837
EMBL· GenBank· DDBJ
BAH11075.1
EMBL· GenBank· DDBJ
Genomic DNA
AP012388
EMBL· GenBank· DDBJ
BAM25624.1
EMBL· GenBank· DDBJ
Genomic DNA
MK128801
EMBL· GenBank· DDBJ
QBB87309.1
EMBL· GenBank· DDBJ
Genomic DNA
MH499873
EMBL· GenBank· DDBJ
QBX96144.1
EMBL· GenBank· DDBJ
Genomic DNA
MG778671
EMBL· GenBank· DDBJ
QEU53525.1
EMBL· GenBank· DDBJ
Genomic DNA
MT418944
EMBL· GenBank· DDBJ
QMP90801.1
EMBL· GenBank· DDBJ
Genomic DNA
MT506309
EMBL· GenBank· DDBJ
QPF98784.1
EMBL· GenBank· DDBJ
Genomic DNA
MK795832
EMBL· GenBank· DDBJ
QQP22635.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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